ArticleThe Plant cell2007
The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.
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Who cites it
124 citing papers in PubMed, 290 citations in OpenAlex.
- AhIRX7, a novel glycosyltransferases (GTs) gene, confers salt and drought tolerance in transgenic peanut.BMC plant biology · 2026Article
- Whole-genome sequences confirm Castilleja lassenensis (Orobanchaceae) as a distinct species from Castilleja lemmonii.The Journal of heredity · 2026Article
- Three Orobanche genomes reveal distinct molecular repertoires in species with different host ranges.Plant & cell physiology · 2026Article
- Overexpression of a Xylem-Dominant Expressing BTB Gene,Plants (Basel, Switzerland) · 2025Article
- Temporal and spatial distribution of pectin, β(1-4)-galactan, xylan and lignin during differentiation of living fibres in young shoots of Leucaena leucocephala (Lam.) de wit.BMC plant biology · 2025Article
- Dual Regulation of Cuticle and Cell Wall Biosynthesis by BnaC9.MYB46 Confers Drought Tolerance in Brassica napus.Plant biotechnology journal · 2025Article
- Rhamnogalacturonan I is a recalcitrant pectin domain during Clostridium thermocellum-mediated deconstruction of switchgrass biomass.Biotechnology for biofuels and bioproducts · 2025Article
- The rice BRITTLE CULM 4 gene encodes a membrane protein affecting cellulose synthesis in the secondary cell wall.Plant & cell physiology · 2025Article
- Genetic dissection of hundred-kernel weight through combined genome-wide association study and linkage analysis in tropical maize.BMC genomics · 2025Article
- Genome-wide identification and expression analysis of theFrontiers in plant science · 2025Article
- Modification of xylan in secondary walls alters cell wall biosynthesis and wood formation programs and improves saccharification.Plant biotechnology journal · 2025Article
- Comprehensive genome-wide identification and functional analysis of the GT8 gene family inFrontiers in plant science · 2025Article
- Article
- Integrated Multi-Omics Analysis to Reveal the Molecular Mechanisms of Inflorescence Elongation inInternational journal of molecular sciences · 2024Article
- Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly inPlant direct · 2024Article
- Integrity of xylan backbone affects plant responses to drought.Frontiers in plant science · 2024Article
- Ectopic callose deposition into woody biomass modulates the nano-architecture of macrofibrils.Nature plants · 2023Article
- A point mutation in the kinase domain of CRK10 leads to xylem vessel collapse and activation of defence responses in Arabidopsis.Journal of experimental botany · 2023Article
- Article
- Identification and bioinformatic analysis of the CaCesA/Csls family members and the expression of the CaCslD1 in the flower buds of CMS/Rf system in pepper.Functional & integrative genomics · 2022Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The secondary cell wall in higher plants consists mainly of cellulose, lignin, and xylan and is the major component of biomass in many species. The Arabidopsis thaliana irregular xylem8 (irx8) mutant is dwarfed and has a significant reduction in secondary cell wall thickness. IRX8 belongs to a subgroup of glycosyltransferase family 8 called the GAUT1-related gene family, whose members include GAUT1, a homogalacturonan galacturonosyltransferase, and GAUT12 (IRX8). Here, we use comparative cell wall analyses to show that the irx8 mutant contains significantly reduced levels of xylan and homogalacturonan. Immunohistochemical analyses confirmed that the level of xylan was significantly reduced in the mutant. Structural fingerprinting of the cell wall polymers further revealed that irx8 is deficient in glucuronoxylan. To explore the biological function of IRX8, we crossed irx8 with irx1 (affecting cellulose synthase 8). The homozygous irx1 irx8 exhibited severely dwarfed phenotypes, suggesting that IRX8 is essential for cell wall integrity during cellulose deficiency. Taken together, the data presented show that IRX8 affects the level of glucuronoxylan and homogalacturonan in higher plants and that IRX8 provides an important link between the xylan polymer and the secondary cell wall matrix and directly affects secondary cell wall integrity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.