ArticlePlant physiology2007
An IRE-like AGC kinase gene, MtIRE, has unique expression in the invasion zone of developing root nodules in Medicago truncatula.
Article in Plant physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Genome-Wide Identification of the AGC Kinase Family in Tetraploid Potato (Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Identification of the AGC Protein Kinase Gene Family Related to Photosynthesis in Rice (International journal of molecular sciences · 2022Article
- Time-course RNA-seq analysis provides an improved understanding of gene regulation during the formation of nodule-like structures in rice.Plant molecular biology · 2020Article
- The Nodule-Specific PLAT Domain Protein NPD1 Is Required for Nitrogen-Fixing Symbiosis.Plant physiology · 2019Article
- Article
- Comparative transcriptome analysis provides key insights into gene expression pattern during the formation of nodule-like structures in Brachypodium.Functional & integrative genomics · 2018Article
- An Iron-Activated Citrate Transporter, MtMATE67, Is Required for Symbiotic Nitrogen Fixation.Plant physiology · 2018Article
- Article
- A Developmental and Molecular View of Formation of Auxin-Induced Nodule-Like Structures in Land Plants.Frontiers in plant science · 2016Article
- Article
- Keel petal incision: a simple and efficient method for genetic crossing in Medicago truncatula.Plant methods · 2014Article
- The identification of novel loci required for appropriate nodule development in Medicago truncatula.BMC plant biology · 2013Article
- cell- and tissue-specific transcriptome analyses of Medicago truncatula root nodules.PloS one · 2013Article
- Functional assessment of the Medicago truncatula NIP/LATD protein demonstrates that it is a high-affinity nitrate transporter.Plant physiology · 2012Article
- A Medicago truncatula tobacco retrotransposon insertion mutant collection with defects in nodule development and symbiotic nitrogen fixation.Plant physiology · 2012Article
- Multiple domains in MtENOD8 protein including the signal peptide target it to the symbiosome.Plant physiology · 2012Article
- Evolutionary Adaptations of Plant AGC Kinases: From Light Signaling to Cell Polarity Regulation.Frontiers in plant science · 2012Article
- Transcription profiling of fertilization and early seed development events in a solanaceous species using a 7.7 K cDNA microarray from Solanum chacoense ovules.BMC plant biology · 2010Article
- EFD Is an ERF transcription factor involved in the control of nodule number and differentiation in Medicago truncatula.The Plant cell · 2008Article
- How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model.Nature reviews. Microbiology · 2007Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The AGC protein kinase family (cAMP-dependent protein kinases A, cGMP-dependent protein kinases G, and phospholipid-dependent protein kinases C) have important roles regulating growth and development in animals and fungi. They are activated via lipid second messengers by 3-phosphoinositide-dependent protein kinase coupling lipid signals to phosphorylation of the AGC kinases. These phosphorylate downstream signal transduction protein targets. AGC kinases are becoming better studied in plants, especially in Arabidopsis (Arabidopsis thaliana), where specific AGC kinases have been shown to have key roles in regulating growth signal pathways. We report here the isolation and characterization of the first AGC kinase gene identified in Medicago truncatula, MtIRE. It was cloned by homology with the Arabidopsis INCOMPLETE ROOT HAIR ELONGATION (IRE) gene. Semiquantitative reverse transcription-polymerase chain reaction analysis shows that, unlike its Arabidopsis counterpart, MtIRE is not expressed in uninoculated roots, but is expressed in root systems that have been inoculated with Sinorhizobium meliloti and are developing root nodules. MtIRE expression is also found in flowers. Expression analysis of a time course of nodule development and of nodulating root systems of many Medicago nodulation mutants shows MtIRE expression correlates with infected cell maturation during nodule development. During the course of these experiments, nine Medicago nodulation mutants, including sli and dnf1 to 7 mutants, were evaluated for the first time for their microscopic nodule phenotype using S. meliloti constitutively expressing lacZ. Spatial localization of a pMtIRE-gusA transgene in transformed roots of composite plants showed that MtIRE expression is confined to the proximal part of the invasion zone, zone II, found in indeterminate nodules. This suggests MtIRE is useful as an expression marker for this region of the invasion zone.
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