ArticleMicrobial cell factories2007
Identification of novel immunogens in Pasteurella multocida.
Article in Microbial cell factories, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
- In silico prediction of Gallibacterium anatis pan-immunogens.Veterinary research · 2014Trial
- In silico design and evaluation of a candidate multiepitope Salmonella vaccine construct targeting broad-spectrum protection in poultry.BMC genomics · 2026Article
- Recent Advances in Bioconjugate Vaccine Development.Vaccines · 2025Review
- Deleting fis downregulates virulence and effectively protects Pasteurella multocida infection in mice.BMC veterinary research · 2025Article
- Evaluation of a multi-epitope vaccine PME forFrontiers in immunology · 2025Article
- Recent Advances in Genomics-Based Approaches for the Development of Intracellular Bacterial Pathogen Vaccines.Pharmaceutics · 2022Review
- Immunogenicity and protective efficacy of the recombinantFrontiers in immunology · 2022Article
- Deleting qseC downregulates virulence and promotes cross-protection in Pasteurella multocida.Veterinary research · 2021Article
- The immune response and protective efficacy of a potential DNA vaccine against virulent Pasteurella multocida.Journal, genetic engineering & biotechnology · 2021Article
- Potential DNA Vaccine for Haemorrhagic Septiceamia Disease.Molecular biotechnology · 2020Article
- Pasteurella multocida: Genotypes and Genomics.Microbiology and molecular biology reviews : MMBR · 2019Review
- Recent Trends in System-Scale Integrative Approaches for Discovering Protective Antigens Against Mycobacterial Pathogens.Frontiers in genetics · 2018Review
- Identification and characterization of a novel stress-responsive outer membrane protein Lip40 from Actinobacillus pleuropneumoniae.BMC biotechnology · 2015Article
- Outer membrane proteome analysis of Indian strain of Pasteurella multocida serotype B:2 by MALDI-TOF/MS analysis.TheScientificWorldJournal · 2014Article
- The fimbrial protein FlfA from Gallibacterium anatis is a virulence factor and vaccine candidate.Infection and immunity · 2013Article
- Comparative genome analysis of an avirulent and two virulent strains of avian Pasteurella multocida reveals candidate genes involved in fitness and pathogenicity.BMC microbiology · 2013Article
- Draft Genome Sequences of Two Virulent Serotypes of Avian Pasteurella multocida.Genome announcements · 2013Article
- Predicting the outer membrane proteome of Pasteurella multocida based on consensus prediction enhanced by results integration and manual confirmation.BMC bioinformatics · 2012Article
- Article
- DraGnET: software for storing, managing and analyzing annotated draft genome sequence data.BMC bioinformatics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledP. multocida is a Gram-negative pathogen responsible for causing diseases in animals of economic significance to livestock industries throughout the world. Current vaccines include bacterins, which provide only limited protection against homologous serotypes. Therefore there is a need for more effective vaccines to control diseases caused by P. multocida. As a step towards developing vaccines against fowl cholera, a genomics based approach was applied for the identification of novel immunogens.
resultsBioinformatics analysis of the P. multocida genome predicted 129 proteins as secreted, located in the outer membrane, or lipoproteins. 105 of the genes encoding these proteins were cloned and recombinant protein expressed in Escherichia coli. Polyclonal serum from P. multocida-infected chickens reacted with a subset of these proteins.
conclusionThese data show the range of bacterial immunogens recognized by the chicken immune system, including 6 novel immunoreactive proteins.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.