Evidence map›Paper›PMID 17230528›Full record

ArticleInternational journal of cancer2007

Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China.

Wang-Hong Xu, Qi Dai, Yong-Bing Xiang, Gen-Ming Zhao, Zhi-Xian Ruan, Jia-Rong Cheng, Wei Zheng, Xiao Ou Shu

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Review
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  13. Review
  14. Phytochemicals in Gynecological Cancer Prevention.International journal of molecular sciences · 2021
    Review
  15. Dietary Reference Values for riboflavin.EFSA journal. European Food Safety Authority · 2017
    Article
  16. Impact of known risk factors on endometrial cancer burden in Chinese women.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2016
    Article
  17. Scientific Opinion on Dietary Reference Values for vitamin E as α-tocopherol.EFSA journal. European Food Safety Authority · 2015
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Wang-Hong XuDepartment of Epidemiology, Fu Dan University School of Public Health, Shanghai, People's Republic of China.
Qi Dai
Yong-Bing Xiang
Gen-Ming Zhao
Zhi-Xian Ruan
Jia-Rong Cheng
Wei Zheng
Xiao Ou Shu
Shanghai Cancer Institute · CNVanderbilt-Ingram Cancer Center

Funding

Soyfood, Gene Polymorphisms and Endometrial Cancer RiskR01CA092585 · NCI · VANDERBILT UNIVERSITY · PI SHU, XIAO-OU · 2001 to 2010
$2.3M
NCI NIH HHS R01 CA092585NCI NIH HHS R01 CA 92585
6 · The paper itself

Abstract

We evaluated the role of dietary nutrients in the etiology of endometrial cancer in a population-based case-control study of 1,204 newly diagnosed endometrial cancer cases and 1,212 age frequency-matched controls. Information on usual dietary habits was collected during an in-person interview using a validated, quantitative food frequency questionnaire. Logistic regression analysis was conducted to evaluate the association of nutrients with endometrial cancer risk using an energy density method (e.g., nutrient intake/1,000 kilocalories of intake). Higher energy intake was associated with increased risk, which was attributable to animal source energy and a high proportion of energy from protein and fat. Odds ratios comparing highest versus lowest quintiles of intake were elevated for intake of animal protein (Odds ratio (OR) = 2.0, 95% confidential interval: 1.5-2.7) and fat (OR = 1.5, 1.2-2.0), but reduced for plant sources of these nutrients (OR = 0.7, 0.5-0.9 for protein and OR = 0.6, 0.5-0.8 for fat). Further analysis showed that saturated and monounsaturated fat intake was associated with elevated risk, while polyunsaturated fat intake was unrelated to risk. Dietary retinol, beta-carotene, vitamin C, vitamin E, fiber, and vitamin supplements were inversely associated with risk. No significant association was observed for dietary vitamin B1 or vitamin B2. Our findings suggest that associations of dietary macronutrients with endometrial cancer risk may depend on their sources, with intake of animal origin nutrients being related to higher risk and intake of plant origin nutrients related to lower risk. Dietary fiber, retinol, beta-carotene, vitamin C, vitamin E, and vitamin supplementation may decrease the risk of endometrial cancer.

Indexed as

DietAdultAgedCase-Control StudiesChinaDiet SurveysEndometrial NeoplasmsFemaleHumansMaleMiddle AgedRisk FactorsSurveys and Questionnaires

Identifiers

PMID17230528
PMCPMC2039904
OpenAlexW2162608769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.