Evidence map›Paper›PMID 17227009›Full record

ArticleJournal of the American Chemical Society2007

A conformational switch to beta-sheet structure in cytochrome c leads to heme exposure. Implications for cardiolipin peroxidation and apoptosis.

Gurusamy Balakrishnan, Ying Hu, Oyeyemi F Oyerinde, Jia Su, John T Groves, Thomas G Spiro

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cytochrome c causes pore formation in cardiolipin-containing membranes.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Conformational properties of cardiolipin-bound cytochrome c.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gurusamy BalakrishnanDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
Ying Hu
Oyeyemi F Oyerinde
Jia Su
John T Groves
Thomas G Spiro

Funding

ULTRAVIOLET RAMAN STUDIES OF PROTEINS AND NUCLEIC ACIDSR01GM025158 · NIGMS · UNIVERSITY OF WASHINGTON · PI SPIRO, THOMAS G. · 1985 to 2014
$5.1M
Molecular Probes of the Mechanisms of Cytocrhome P450R37GM036298 · NIGMS · PRINCETON UNIVERSITY · PI GROVES, JOHN TAYLOR · 2007 to 2016
$3.7M
HEME PROTEIN STRUCTURE AND DYNAMICSR01GM033576 · NIGMS · UNIVERSITY OF WASHINGTON · PI SPIRO, THOMAS G. · 1985 to 2010
$3.5M
Molecular Probes of the Mechanisms of Cytochrome P450R01GM036298 · NIGMS · PRINCETON UNIVERSITY · PI GROVES, JOHN TAYLOR · 1986 to 2006
$2.4M
NIGMS NIH HHS GM 036298NIGMS NIH HHS GM 25158NIGMS NIH HHS R01 GM025158NIGMS NIH HHS R01 GM033576NIGMS NIH HHS R01 GM036298NIGMS NIH HHS R37 GM036298
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisCardiolipinsCytochromes cHemeHydrogen-Ion ConcentrationIronModels, MolecularPeroxidasesPeroxidesProtein Structure, SecondarySpectrum Analysis, RamanTemperatureCardiolipinsCytochromes cHemeIronPeroxidasesPeroxides

Identifiers

PMID17227009
PMCPMC2596592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.