Evidence map›Paper›PMID 17226053›Full record

ReviewPflugers Archiv : European journal of physiology2007

Even a stopped clock tells the right time twice a day: circadian timekeeping in Drosophila.

Ben Collins, Justin Blau

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Evidence thatbioRxiv : the preprint server for biology · 2025
    Article
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  5. The genetics of behavioral alcohol responses in Drosophila.International review of neurobiology · 2010
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ben CollinsDepartment of Biology, New York University, 100 Washington Square East, New York, NY 10003, USA.
Justin Blau
New York University · US

Funding

Regulation of pacemaker neuronsR01GM063911 · NIGMS · NEW YORK UNIVERSITY · PI BLAU, JUSTIN · 2002 to 2019
$5.6M
6 · The paper itself

Abstract

"Even a stopped clock tells the right time twice a day, and for once I'm inclined to believe Withnail is right. We are indeed drifting into the arena of the unwell... What we need is harmony. Fresh air. Stuff like that" "Bruce Robinson (1986, ref. 1)". Although a stopped Drosophila clock probably does not tell the right time even once a day, recent findings have demonstrated that accurate circadian time-keeping is dependent on harmony between groups of clock neurons within the brain. Furthermore, when harmony between the environment and the endogenous clock is lost, as during jet lag, we definitely feel unwell. In this review, we provide an overview of the current understanding of circadian rhythms in Drosophila, focussing on recent discoveries that demonstrate how approximately 100 neurons within the Drosophila brain control the behaviour of the whole fly, and how these rhythms respond to the environment.

Indexed as

Adaptation, BiologicalAnimalsBiological ClocksCircadian RhythmDrosophilaDrosophila ProteinsFeedback, PhysiologicalGenes, InsectLightModels, NeurologicalMutagenesis, Site-DirectedNerve NetPhotoreceptor Cells, InvertebrateThermosensingDrosophila Proteins

Identifiers

PMID17226053
OpenAlexW1986451014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.