ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life2007
The sugar model: autocatalytic activity of the triose-ammonia reaction.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 46 citations in OpenAlex.
- Can the origin of biosynthetic routes be explained by a Frankenstein's monster-like spontaneous assembly of prebiotic reactants?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Rethinking life and predicting its origin.Theory in biosciences = Theorie in den Biowissenschaften · 2024Article
- Stability of DL-Glyceraldehyde under Simulated Hydrothermal Conditions: Synthesis of Sugar-like Compounds in an Iron(III)-Oxide-Hydroxide-Rich Environment under Acidic Conditions.Life (Basel, Switzerland) · 2022Article
- On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2022Review
- Self-Reproduction and Darwinian Evolution in Autocatalytic Chemical Reaction Systems.Life (Basel, Switzerland) · 2021Review
- Coenzymes and Their Role in the Evolution of Life.Angewandte Chemie (International ed. in English) · 2021Review
- Is boron a prebiotic element? A mini-review of the essentiality of boron for the appearance of life on earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2012Review
- Planetary organic chemistry and the origins of biomolecules.Cold Spring Harbor perspectives in biology · 2010Article
- Sugar-driven prebiotic synthesis of ammonia from nitrite.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2010Article
- Bioenergetics and life's origins.Cold Spring Harbor perspectives in biology · 2010Review
- Sugar-driven prebiotic synthesis of 3,5(6)-dimethylpyrazin-2-one: a possible nucleobase of a primitive replication process.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2008Article
- The implausibility of metabolic cycles on the prebiotic Earth.PLoS biology · 2008Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reaction of triose sugars with ammonia under anaerobic conditions yielded autocatalytic products. The autocatalytic behavior of the products was examined by measuring the effect of the crude triose-ammonia reaction product on the kinetics of a second identical triose-ammonia reaction. The reaction product showed autocatalytic activity by increasing both the rate of disappearance of triose and the rate of formation of pyruvaldehyde, the product of triose dehydration. This synthetic process is considered a reasonable model of origin-of-life chemistry because it uses plausible prebiotic substrates, and resembles modern biosynthesis by employing the energized carbon groups of sugars to drive the synthesis of autocatalytic molecules.
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