ReviewClinical and experimental immunology2007
Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders.
Review in Clinical and experimental immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- A study of the key genes and inflammatory signaling pathways involved in HLA-B27-associated acute anterior uveitis families.International journal of molecular medicine · 2018Article
- Article
- Innate immune response of alveolar macrophage to house dust mite allergen is mediated through TLR2/-4 co-activation.PloS one · 2013Article
- Adjuvants for allergy vaccines.Human vaccines & immunotherapeutics · 2012Review
- Endotoxin as a determinant of asthma and wheeze among rural dwelling children and adolescents: a case-control study.BMC pulmonary medicine · 2012Article
- Inflammation and adaptive immunity in Parkinson's disease.Cold Spring Harbor perspectives in medicine · 2012Review
- The interferon-alpha and interleukin-10 responses in neonates differ from adults, and their production remains partial throughout the first 18 months of life.Clinical and experimental immunology · 2010Article
- Functional aspects of Toll-like receptor/MyD88 signalling during protozoan infection: focus on Toxoplasma gondii.Clinical and experimental immunology · 2009Review
- Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation.Journal of immunological methods · 2008Article
- Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma.European journal of immunology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Characterization of the Toll-like receptor (TLR) family and associated signalling pathways provides a key molecular basis for our understanding of the relationship between exposure to microbial products and susceptibility to immune-mediated disorders. Indeed, ligation of TLR controls innate and adaptive immune responses by inducing synthesis of pro- as well as anti-inflammatory cytokines and activation of effector as well as regulatory lymphocytes. TLRs are therefore considered as major targets for the development of vaccine adjuvants, but also of new immunotherapies. Herein, we review the potential of TLR ligands as a novel class of pharmaceuticals for the prevention or treatment of allergic disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.