ArticleLancet (London, England)2007
Syphilis in China: results of a national surveillance programme.
Article in Lancet (London, England), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 11 of them syntheses that pooled it.
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Who cites it
152 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta-analysis.Journal of the International AIDS Society · 2025Pooled it
- Epidemiology ofJournal of global health · 2019Pooled it
- A spatiotemporal meta-analysis of HIV/syphilis epidemic among men who have sex with men living in mainland China.BMC infectious diseases · 2018Pooled it
- Trends and Predictors of Syphilis Prevalence in the General Population: Global Pooled Analyses of 1103 Prevalence Measures Including 136 Million Syphilis Tests.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Pooled it
- Syphilis incidence among men who have sex with men in China: results from a meta-analysis.International journal of STD & AIDS · 2017Pooled it
- Safety of benzathine penicillin for preventing congenital syphilis: a systematic review.PloS one · 2013Pooled it
- Sexually transmitted infections among heterosexual male clients of female sex workers in China: a systematic review and meta-analysis.PloS one · 2013Pooled it
- Pooled it
- Molecular typing of Treponema pallidum: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2011Pooled it
- HIV and syphilis co-infection increasing among men who have sex with men in China: a systematic review and meta-analysis.PloS one · 2011Pooled it
- Antibiotics for syphilis diagnosed during pregnancy.The Cochrane database of systematic reviews · 2001Pooled it
- An Incognito Standardized Patient Approach for Measuring and Reducing Intersectional Healthcare Stigma: A Pilot Cluster Randomized Control Trial.Journal of acquired immune deficiency syndromes (1999) · 2025Trial
- Trial
- Trial
- Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report.Experimental and therapeutic medicine · 2026Article
- Incognito Standardized Patients to Assess Physician Awareness and Capacity to Recognize Primary Syphilis Presentation in Chinese STI Clinics.Sexually transmitted diseases · 2026Article
- Socioeconomic transitions and the spatial dynamics of syphilis transmission in urbanizing China.International journal for equity in health · 2026Article
- Epidemiological characteristics of syphilis in China from 2005 to 2020: predominance of latent Infections, significant burden in the elderly population, and analysis of regional disparities.BMC public health · 2025Article
- The changing epidemiology of syphilis: new strategies for new challenges in China.The Lancet regional health. Western Pacific · 2025Review
- Epidemiological characteristics and socioeconomic factors of sexually transmitted infections in China during 2002-2021.BMC public health · 2025Article
92 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAfter a massive syphilis epidemic in the first half of the 20th century, China was able to eliminate this infection for 20 years (1960-80). However, substantial changes in Chinese society have been followed by a resurgent epidemic of sexually transmitted diseases. Sporadic reports have provided clues to the magnitude of the spread of syphilis, but a national surveillance effort is needed to provide data for planning and intervention.
methodsWe collected and assessed case report data from China's national sexually transmitted disease surveillance system and sentinel site network.
findingsIn 1993, the reported total rate of cases of syphilis in China was 0.2 cases per 100,000, whereas primary and secondary syphilis alone represented 5.7 cases per 100,000 persons in 2005. The rate of congenital syphilis increased greatly with an average yearly rise of 71.9%, from 0.01 cases per 100,000 livebirths in 1991 to 19.68 cases per 100 000 livebirths in 2005.
interpretationThe results suggest that a range of unique biological and social forces are driving the spread of syphilis in China. A national campaign for detection and treatment of syphilis, and a credible prevention strategy, are urgently needed.
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