ArticlePLoS genetics2007
Comparative genomics of large mitochondria in placozoans.
Article in PLoS genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 114 citations in OpenAlex.
- Towards a mitogenomic phylogeny of mud dragons (Kinorhyncha): two new mitogenomes from the Pycnophyidae family.Scientific reports · 2026Article
- Beauty in the beast - Placozoan biodiversity explored through molluscan predator genomics.Ecology and evolution · 2024Article
- Article
- Confirmation of the first intronic sequence in the bivalvian mitochondrial genome ofBiology letters · 2022Article
- Unprecedented frequency of mitochondrial introns in colonial bilaterians.Scientific reports · 2022Article
- Article
- Mitochondrial Genomic Landscape: A Portrait of the Mitochondrial Genome 40 Years after the First Complete Sequence.Life (Basel, Switzerland) · 2021Article
- Morphological Characters Can Strongly Influence Early Animal Relationships Inferred from Phylogenomic Data Sets.Systematic biology · 2021Article
- Mitochondrial Genome Evolution of Placozoans: Gene Rearrangements and Repeat Expansions.Genome biology and evolution · 2021Article
- Insights into the origin of metazoan multicellularity from predatory unicellular relatives of animals.BMC biology · 2020Article
- Article
- Genome streamlining via complete loss of introns has occurred multiple times in lichenized fungal mitochondria.Ecology and evolution · 2019Article
- Bioeffects ofPeerJ · 2019Article
- Article
- Comparative genomics and the nature of placozoan species.PLoS biology · 2018Article
- Intercompartmental Piecewise Gene Transfer.Genes · 2017Review
- MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis.Scientific reports · 2017Article
- Evolution of group I introns in Porifera: new evidence for intron mobility and implications for DNA barcoding.BMC evolutionary biology · 2017Article
- The most primitive metazoan animals, the placozoans, show high sensitivity to increasing ocean temperatures and acidities.Ecology and evolution · 2017Article
- Deep RNA sequencing reveals the smallest known mitochondrial micro exon in animals: The placozoan cox1 single base pair exon.PloS one · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The first sequenced mitochondrial genome of a placozoan, Trichoplax adhaerens, challenged the conventional wisdom that a compact mitochondrial genome is a common feature among all animals. Three additional placozoan mitochondrial genomes representing highly divergent clades have been sequenced to determine whether the large Trichoplax mtDNA is a shared feature among members of the phylum Placozoa or a uniquely derived condition. All three mitochondrial genomes were found to be very large, 32- to 37-kb, circular molecules, having the typical 12 respiratory chain genes, 24 tRNAs, rnS, and rnL. They share with the Trichoplax mitochondrial genome the absence of atp8, atp9, and all ribosomal protein genes, the presence of several cox1 introns, and a large open reading frame containing an intron group I LAGLIDADG endonuclease domain. The differences in mtDNA size within Placozoa are due to variation in intergenic spacer regions and the presence or absence of long open reading frames of unknown function. Phylogenetic analyses of the 12 respiratory chain genes support the monophyly of Placozoa. The similarities in composition and structure between the three mitochondrial genomes reported here and that of Trichoplax's mtDNA suggest that their uncompacted state is a shared ancestral feature to other nonmetazoans while their gene content is a derived feature shared only among the Metazoa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.