Evidence map›Paper›PMID 17221065›Full record

ReviewBrazilian journal of otorhinolaryngology

Oral complications of radiotherapy in the head and neck.

Bruno Correia Jham, Addah Regina da Silva Freire

Registry-linked trialAbstract readReview
In one paragraph

Review in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03753932 (Patients With Head and Neck Cancer Treated by Radiotherapy), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03753932 nacompletednot on this map

Patients With Head and Neck Cancer Treated by Radiotherapy: The Impact of Fixed Dentures on Wellbeing and Oral Health Related Quality of Life

TypeinterventionalSponsorRegion Jönköping CountyRan2013 to 2021Enrolled64ConditionsHead and Neck Neoplasms, Dental Prosthesis, Dentures, Quality of LifeArmsFixed prosthodontics
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Post-radiotherapy xerostomia and quality of life in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The intra-oral variation of salivary ions.Clinical oral investigations · 2025
    Article
  15. Oropharyngeal candidiasis during radiotherapy for head and neck cancer: an observational study on prevalence, pain, and risk factors.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Observational
  16. Article
  17. Characterization of irradiated mucosa using confocal laser endomicroscopy in the upper aerodigestive tract.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bruno Correia JhamFaculdade de Odontologia, Universidade Federal de Minas Gerais, Brazil.
Addah Regina da Silva Freire

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledRadiotherapy is a treatment modality largely used for head and neck malignancies. However, high doses of radiation in large areas, including the oral cavity, maxilla, mandible and salivary glands may result in several undesired reactions. Mucositis, candidosis, disgeusia, radiation caries, osteoradionecrosis, soft tissue necrosis and xerostomia are some of radiotherapys complications.

aimThe aim of this study is to briefly review the side effects that may be seen in the oral cavity during or after radiotherapy treatment in the head and neck region. BASIC METHOD USED: Review of relevant literature. STUDY

designLiterature review.

resultsRadiotherapy is still associated with several side effects, significantly affecting patients quality of life.

conclusionsA multidisciplinary treatment, including physicians, dentists, speech therapists, nutritionists, and psychologists, is the best alternative to minimize, or even prevent such reactions.

Indexed as

Cranial IrradiationDental CariesHead and Neck NeoplasmsHumansJaw DiseasesMouth DiseasesMouth MucosaOsteoradionecrosisQuality of LifeRadiation Injuries

Identifiers

PMID17221065
PMCPMC9443542

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.