ReviewMolecular neurobiology2006
Nicotine and hippocampus-dependent learning: implications for addiction.
Review in Molecular neurobiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 62 citations in OpenAlex.
- Addressing Altered Anticipation as a Transdiagnostic Target Through Computational Psychiatry.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Review
- Article
- Patterns and Characteristics of Nicotine Dependence Among Adults With Cigarette Use in the US, 2006-2019.JAMA network open · 2023Article
- Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.Molecular psychiatry · 2022Article
- The impact of adolescent stress on nicotine use and affective disorders in rodent models.The European journal of neuroscience · 2022Review
- Article
- Tobacco Smoking and Brain Endogenous Opioid Release: More Than Nicotine Alone.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning.Neuropharmacology · 2017Article
- Effectiveness of a Novel Qigong Meditative Movement Practice for Impaired Health in Flight Attendants Exposed to Second-Hand Cigarette Smoke.Frontiers in human neuroscience · 2017Article
- α2-Null mutant mice have altered levels of neuronal activity in restricted midbrain and limbic brain regions during nicotine withdrawal as demonstrated by cfos expression.Biochemical pharmacology · 2015Article
- Thyroid hormone signaling: Contribution to neural function, cognition, and relationship to nicotine.Neuroscience and biobehavioral reviews · 2015Review
- Thyroid receptor β involvement in the effects of acute nicotine on hippocampus-dependent memory.Neuropharmacology · 2015Article
- ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice.Behavioural pharmacology · 2015Article
- Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system.Journal of neuroscience research · 2015Article
- Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.Acta neuropathologica communications · 2014Article
- Donepezil reverses nicotine withdrawal-induced deficits in contextual fear conditioning in C57BL/6J mice.Behavioral neuroscience · 2014Article
- Involvement of neuronal β2 subunit-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal: implications for pharmacotherapies.Journal of clinical pharmacy and therapeutics · 2014Review
- Substance abuse, memory, and post-traumatic stress disorder.Neurobiology of learning and memory · 2014Review
- Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Tobacco addiction and the dysregulation of brain stress systems.Neuroscience and biobehavioral reviews · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Addiction is a complex disorder because many factors contribute to the development and maintenance of addiction. One factor is learning. For example, drug-context associations that develop during drug use could facilitate drug craving upon re-exposure to contexts previously associated with drugs. Additionally, deficits in cognitive processes associated with withdrawal could precipitate relapse in attempts to ameliorate those deficits. Because addiction and learning involve common neural areas and cell signaling cascades, addiction-related changes in processes underlying plasticity may contribute to addiction. This article examines similarities between addiction and learning at the behavioral, neural, and cellular levels, with emphasis on the neural substrates underlying the effects of acute nicotine, chronic nicotine, and withdrawal from chronic nicotine on hippocampus-dependent contextual learning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.