ArticlePlant physiology2007
The lipopolysaccharide of Sinorhizobium meliloti suppresses defense-associated gene expression in cell cultures of the host plant Medicago truncatula.
Article in Plant physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 112 citations in OpenAlex.
- Lipopolysaccharide hydrolysis-targeting nano-chimeras detoxify endotoxin through specific adsorption and efficient degradation.Nature communications · 2026Article
- Comparative genomic and transcriptomic analyses provide new insight into symbiotic host specificity.iScience · 2024Article
- Comprehensive identification of maize ZmE2F transcription factors and the positive role of ZmE2F6 in response to drought stress.BMC genomics · 2024Article
- A Germin-Like Protein GLP1 of Legumes Mediates Symbiotic Nodulation by Interacting with an Outer Membrane Protein of Rhizobia.Microbiology spectrum · 2023Article
- Localized osmotic stress activates systemic responses to N limitation inFrontiers in plant science · 2023Article
- Varietas Delectat: Exploring Natural Variations in Nitrogen-Fixing Symbiosis Research.Frontiers in plant science · 2022Review
- Legume-rhizobium dance: an agricultural tool that could be improved?Microbial biotechnology · 2021Review
- Plant Immune Mechanisms: From Reductionistic to Holistic Points of View.Molecular plant · 2020Review
- Beneficial microbes going underground of root immunity.Plant, cell & environment · 2019Review
- Expression of the Arabidopsis thaliana immune receptor EFR in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen-fixing rhizobial symbiosis.Plant biotechnology journal · 2019Article
- Genetic and Molecular Mechanisms Underlying Symbiotic Specificity in Legume-Rhizobium Interactions.Frontiers in plant science · 2018Review
- Interplay of Pathogen-Induced Defense Responses and Symbiotic Establishment inFrontiers in microbiology · 2017Article
- Transcriptional regulator LsrB of Sinorhizobium meliloti positively regulates the expression of genes involved in lipopolysaccharide biosynthesis.Applied and environmental microbiology · 2014Article
- Unexpectedly low nitrogen acquisition and absence of root architecture adaptation to nitrate supply in a Medicago truncatula highly branched root mutant.Journal of experimental botany · 2014Article
- Immunosuppression during Rhizobium-legume symbiosis.Plant signaling & behavior · 2014Article
- Maize root lectins mediate the interaction with Herbaspirillum seropedicae via N-acetyl glucosamine residues of lipopolysaccharides.PloS one · 2013Article
- The non-specific lipid transfer protein N5 of Medicago truncatula is implicated in epidermal stages of rhizobium-host interaction.BMC plant biology · 2012Article
- Two direct targets of cytokinin signaling regulate symbiotic nodulation in Medicago truncatula.The Plant cell · 2012Article
- The Choice between MapMan and Gene Ontology for Automated Gene Function Prediction in Plant Science.Frontiers in genetics · 2012Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the establishment of symbiosis between Medicago truncatula and the nitrogen-fixing bacterium Sinorhizobium meliloti, the lipopolysaccharide (LPS) of the microsymbiont plays an important role as a signal molecule. It has been shown in cell cultures that the LPS is able to suppress an elicitor-induced oxidative burst. To investigate the effect of S. meliloti LPS on defense-associated gene expression, a microarray experiment was performed. For evaluation of the M. truncatula microarray datasets, the software tool MapMan, which was initially developed for the visualization of Arabidopsis (Arabidopsis thaliana) datasets, was adapted by assigning Medicago genes to the ontology originally created for Arabidopsis. This allowed functional visualization of gene expression of M. truncatula suspension-cultured cells treated with invertase as an elicitor. A gene expression pattern characteristic of a defense response was observed. Concomitant treatment of M. truncatula suspension-cultured cells with invertase and S. meliloti LPS leads to a lower level of induction of defense-associated genes compared to induction rates in cells treated with invertase alone. This suppression of defense-associated transcriptional rearrangement affects genes induced as well as repressed by elicitation and acts on transcripts connected to virtually all kinds of cellular processes. This indicates that LPS of the symbiont not only suppresses fast defense responses as the oxidative burst, but also exerts long-term influences, including transcriptional adjustment to pathogen attack. These data indicate a role for LPS during infection of the plant by its symbiotic partner.
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