Evidence map›Paper›PMID 17219027›Full record

ArticlePediatric cardiology

Noninvasive cerebral oximeter as a surrogate for mixed venous saturation in children.

Adnan T Bhutta, Jesse W Ford, James G Parker, Parthak Prodhan, Eudice E Fontenot, Paul M Seib, Brittany I Stroope, Elizabeth A Frazier, Michael L Schmitz, Jonathan J Drummond-Webb and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 72 citations in OpenAlex.

  1. Trial
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  4. Observational
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  11. Neurophotonics · 2018
    Review
  12. Observational
  13. Article
  14. Article
  15. Cerebral and tissue oximetry.Best practice & research. Clinical anaesthesiology · 2014
    Review
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Adnan T BhuttaDepartment of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, AR 72202, USA. bhuttaadnant@uams.edu
Jesse W Ford
James G Parker
Parthak Prodhan
Eudice E Fontenot
Paul M Seib
Brittany I Stroope
Elizabeth A Frazier
Michael L Schmitz
Jonathan J Drummond-Webb
William R Morrow
University of Arkansas for Medical Sciences · USArkansas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the relationship between regional cerebral oxygen saturation (rSO(2)) measured by near-infrared spectroscopy (NIRS) cerebral oximeter with superior vena cava (SVC), inferior vena cava (IVC), right atrium (RA), and pulmonary artery (PA) saturation measured on room air and 100% inspired oxygen administered via a non-rebreather mask (NRB) in children. Twenty nine pediatric post-orthotopic heart transplant patients undergoing an annual myocardial biopsy were studied. We found a statistically significant correlation between rSO(2) and SVC saturations at room air and 100% inspired oxygen concentration via NRB (r = 0.67, p = 0.0002 on room air; r = 0.44, p = 0.02 on NRB), RA saturation (r = 0.56, p = 0.002; r = 0.56, p = 0.002), and PA saturation (r = 0.67, p < 0.001; r = 0.4, p = 0.03). A significant correlation also existed between rSO(2) and measured cardiac index (r = 0.45, p = 0.01) and hemoglobin levels (r = 0.41, p = 0.02). The concordance correlations were fair to moderate. Bias and precision of rSO(2) compared to PA saturations on room air were -0.8 and 13.9%, and they were 2.1 and 15.6% on NRB. A stepwise linear regression analysis showed that rSO(2) saturations were the best predictor of PA saturations on both room air (p = 0.0001) and NRB (p = 0.012). In children with biventricular anatomy, rSO(2) readings do correlate with mixed venous saturation.

Indexed as

OximetryOxygen ConsumptionAdolescentAge FactorsCardiac CatheterizationCerebral CortexCerebrovascular CirculationChildChild, PreschoolFemaleHeart TransplantationHumansInfantMalePostoperative PeriodSpectroscopy, Near-Infrared

Identifiers

PMID17219027
OpenAlexW2070177730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.