Trial reportAmerican journal of preventive medicine2007
Preventing alcohol-exposed pregnancies: a randomized controlled trial.
Trial report in American journal of preventive medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 115 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 13 syntheses or guidelines pooled it, 301 citations in OpenAlex.
- Motivational interviewing for substance use reduction.The Cochrane database of systematic reviews · 2023Pooled it
- Effectiveness of brief alcohol interventions for pregnant women: a systematic literature review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Effectiveness of preconception interventions in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022Pooled it
- Why do women consume alcohol during pregnancy or while breastfeeding?Drug and alcohol review · 2022Pooled it
- Theory-based interventions for contraception.The Cochrane database of systematic reviews · 2016Pooled it
- Pooled it
- Preconception care: caffeine, smoking, alcohol, drugs and other environmental chemical/radiation exposure.Reproductive health · 2014Pooled it
- Preconception healthcare and congenital disorders: systematic review of the effectiveness of preconception care programs in the prevention of congenital disorders.Maternal and child health journal · 2014Pooled it
- Brief intervention and decrease of alcohol consumption among women: a systematic review.Substance abuse treatment, prevention, and policy · 2013Pooled it
- Strategies for communicating contraceptive effectiveness.The Cochrane database of systematic reviews · 2013Pooled it
- Motivational interviewing for substance abuse.The Cochrane database of systematic reviews · 2011Pooled it
- Routine pre-pregnancy health promotion for improving pregnancy outcomes.The Cochrane database of systematic reviews · 2009Pooled it
- Psychological and/or educational interventions for reducing alcohol consumption in pregnant women and women planning pregnancy.The Cochrane database of systematic reviews · 2009Pooled it
- Examining the role of social determinants of health in alcohol-exposed pregnancy risk among American Indian women.BMC women's health · 2025Trial
- Preconception Maternal Mentoring for Improved Fetal Growth among Indonesian Women: Results from a Cluster Randomized Controlled Trial.Nutrients · 2023Trial
- Motivational interviewing for family planning and reducing risky sexual behavior among incarcerated men nearing release: A randomized controlled pilot study.Psychological services · 2023Trial
- A survey with interventional components delivered on tablet devices versus usual care to increase pre-exposure prophylaxis uptake among cisgender Black women: a pilot randomized controlled trial.BMC infectious diseases · 2023Trial
- Motivational interviewing to reduce risky sexual behaviors among at-risk male youth: A randomized controlled pilot study.Psychological services · 2022Trial
- Profiles of behavior change constructs for reducing alcohol use in women at risk of an alcohol-exposed pregnancy.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018Trial
- A practice change intervention to improve antenatal care addressing alcohol consumption by women during pregnancy: research protocol for a randomised stepped-wedge cluster trial.Implementation science : IS · 2018Trial
55 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedJohnson, Kenneth [added]
Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundPrenatal alcohol exposure is a leading preventable cause of birth defects and developmental disabilities in the United States.
designA randomized controlled trial (2002-2005; data analyzed 2005-2006) of a brief motivational intervention to reduce the risk of an alcohol-exposed pregnancy (AEP) in preconceptional women by focusing on both risk drinking and ineffective contraception use. SETTING/
participantsA total of 830 nonpregnant women, aged 18-44 years, and currently at risk for an AEP were recruited in six diverse settings in Florida, Texas, and Virginia. Combined settings had higher proportions of women at risk for AEP (12.5% overall) than in the general population (2%).
interventionsParticipants were randomized to receive information plus a brief motivational intervention (n=416) or to receive information only (n=414). The brief motivational intervention consisted of four counseling sessions and one contraception consultation and services visit.
main outcome measuresWomen consuming more than five drinks on any day or more than eight drinks per week on average, were considered risk drinkers; women who had intercourse without effective contraception were considered at risk of pregnancy. Reversing either or both risk conditions resulted in reduced risk of an AEP.
resultsAcross the follow-up period, the odds ratios (ORs) of being at reduced risk for AEP were twofold greater in the intervention group: 3 months, 2.31 (95% confidence interval [CI]=1.69-3.20); 6 months, 2.15 (CI=1.52-3.06); 9 months, 2.11 (CI=1.47-3.03). Between-groups differences by time phase were 18.0%, 17.0%, and 14. 8%, respectively.
conclusionsA brief motivational intervention can reduce the risk of an AEP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.