ArticleNeoplasia (New York, N.Y.)2006
Genomic profiling of hormone-naïve lymph node metastases in patients with prostate cancer.
Article in Neoplasia (New York, N.Y.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Identification of ovarian cancer metastatic miRNAs.PloS one · 2013Trial
- Low endogenous testosterone levels are associated with the extend of lymphnodal invasion at radical prostatectomy and extended pelvic lymph node dissection.International urology and nephrology · 2021Article
- The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial-to-mesenchymal transition and lipid-derived energy production in prostate cancer cells.Molecular oncology · 2020Article
- Endogenous testosterone mirrors prostate cancer aggressiveness: correlation between basal testosterone serum levels and prostate cancer European Urology Association clinical risk classes in a large cohort of Caucasian patients.International urology and nephrology · 2020Article
- Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease.PloS one · 2014Article
- Biological resonance for cancer metastasis, a new hypothesis based on comparisons between primary cancers and metastases.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2013Article
- Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.Nature communications · 2013Article
- Challenges in identifying candidate amplification targets in human cancers: chromosome 8q21 as a case study.Genes & cancer · 2012Article
- Article
- DNA copy number aberrations in breast cancer by array comparative genomic hybridization.Genomics, proteomics & bioinformatics · 2009Article
- Neoplasia: the second decade.Neoplasia (New York, N.Y.) · 2008Article
- Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.Neoplasia (New York, N.Y.) · 2008Article
- High resolution oligonucleotide CGH using DNA from archived prostate tissue.The Prostate · 2007Article
- Basal total testosterone serum levels predict biopsy and pathological ISUP grade group in a large cohort of Caucasian prostate cancer patients who underwent radical prostatectomy.Therapeutic advances in urologyArticle
- High body mass index predicts multiple prostate cancer lymph node metastases after radical prostatectomy and extended pelvic lymph node dissection.Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The progression of organ-confined prostate cancer to metastatic cancer is inevitably fatal. Consequently, identification of structural changes in the genome and associated transcriptional responses that drive this progression is critical to understanding the disease process and the development of biomarkers and therapeutic targets. In this study, whole genome copy number changes in genomes of hormone-naïve lymph node metastases were profiled using array comparative genomic hybridization, and matched primaries were included for a subset. Matched primaries and lymph node metastases showed very similar copy number profiles that are distinct from primary tumors that fail to metastasize.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.