ArticleClinical drug investigation2007
Retrospective evaluation of adverse drug reactions induced by nonsteroidal anti-inflammatory drugs.
Article in Clinical drug investigation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 67 citations in OpenAlex.
- Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.Clinical interventions in aging · 2014Trial
- Characteristics and clinical implications of the pharmacokinetic profile of ibuprofen in patients with knee osteoarthritis.Clinical drug investigation · 2012Trial
- Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes.European journal of clinical pharmacology · 2010Trial
- Efficacy and Safety of Intra-Articular Therapy with Cross-Linked Hyaluronic Acid in Patients with Knee Osteoarthritis.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Assessing Gender Differences in Neuropathic Pain Management: Findings from a Real-Life Clinical Cross-Sectional Observational Study.Journal of clinical medicine · 2024Article
- The Risk of Drug Interactions in Older Primary Care Patients after Hospital Discharge: The Role of Drug Reconciliation.Geriatrics (Basel, Switzerland) · 2023Article
- The Safety of Drug Treatment in Patients with Neuropathic Pain: Data from Ambulatory Care in a Real-Life Setting.Reports (MDPI) · 2023Article
- The Pharmacological Treatment of Chronic Pain: From Guidelines to Daily Clinical Practice.Pharmaceutics · 2023Review
- FT-IR Analysis of Structural Changes in Ketoprofen Lysine Salt and KiOil Caused by a Pulsed Magnetic Field.Bioengineering (Basel, Switzerland) · 2022Article
- Article
- Drug-Drug Interactions in Vestibular Diseases, Clinical Problems, and Medico-Legal Implications.International journal of environmental research and public health · 2021Review
- Postoperative Nausea and Vomiting in Pediatric Patients.Paediatric drugs · 2021Review
- Hsa-miR-34a-5p and hsa-miR-375 as Biomarkers for Monitoring the Effects of Drug Treatment for Migraine Pain in Children and Adolescents: A Pilot Study.Journal of clinical medicine · 2019Article
- Effects of Add-On Ultramicronized N-Palmitol Ethanol Amide in Patients Suffering of Migraine With Aura: A Pilot Study.Frontiers in neurology · 2018Article
- An integrated safety analysis of intravenous ibuprofen (Caldolor(®)) in adults.Journal of pain research · 2015Article
- Effects of phenobarbital and levetiracetam on PR and QTc intervals in patients with post-stroke seizure.Clinical drug investigation · 2014Article
- Effects of glucocorticoids and tumor necrosis factor-alpha inhibitors on both clinical and molecular parameters in patients with Takayasu arteritis.Journal of pharmacology & pharmacotherapeutics · 2014Article
- Rosacea-like facial rash related to metformin administration in a young woman.BMC pharmacology & toxicology · 2014Article
- Use of ibuprofen sustained release for treating osteoarthritic pain: findings from 15 general medical practices in Egypt.Open access rheumatology : research and reviews · 2014Article
- Retrospective evaluation of adverse drug reactions induced by antihypertensive treatment.Journal of pharmacology & pharmacotherapeutics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveNonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed drugs, and their use can be complicated by the development of adverse drug reactions (ADRs). The aim of this study was to assess the frequency of NSAID-induced ADRs in hospitalised patients in the Clinical Divisions of the Catanzaro and Cosenza hospitals.
methodsWe retrospectively analysed NSAID-induced ADRs after evaluating all ADRs recorded by the Clinical Divisions of the Catanzaro and Cosenza hospitals over a 10-year period, from January 1995 to December 2004.
resultsNSAIDs were found to be responsible for 55.2% of the episodes of ADRs overall. Diclofenac and aspirin (acetylsalicylic acid) were the drugs most frequently involved in the development of ADRs, while the skin was the body system most susceptible to NSAID-induced ADRs (43%). We determined that the drug-ADR relationship was probable in 62% of the reports; withdrawal of NSAID therapy led to a resolution of the clinical features of ADRs in 86% of episodes.
conclusionNSAID therapy represents a common cause of ADRs in hospitalised patients. Their use should be carefully considered, especially in the presence of polydrug therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.