ArticleOrganic letters2007
Phosphatidylcholine-derived bolaamphiphiles via click chemistry.
Article in Organic letters, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- A Lipid-Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells.Angewandte Chemie (International ed. in English) · 2026Article
- 4-Sulfanyl-1,2,3-triazole as a Powerful Ligand in CuAAC to Synthesize 1,4-Substituted 1,2,3-Triazoles Under Solvent-Free and Low Catalyst Loading.Molecules (Basel, Switzerland) · 2026Article
- Circular Dichroism and Multiphoton Circularly Polarized Luminescence Switching Using a Bis-perylene Diimide Macrocycle.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Highly Effective Biocides againstACS infectious diseases · 2024Article
- Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate-Caged Guanidine Lipid.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Development of small-molecule inhibitors of fatty acyl-AMP and fatty acyl-CoA ligases in Mycobacterium tuberculosis.European journal of medicinal chemistry · 2020Article
- Biomedically Relevant Applications of Bolaamphiphiles and Bolaamphiphile-Containing Materials.Frontiers in chemistry · 2020Review
- The medicinal thiosulfinates from garlic andChemical science · 2015Article
- A clickable and photocleavable lipid analogue for cell membrane delivery and release.Bioconjugate chemistry · 2015Article
- Synthesis, surface properties, and biocompatibility of 1,2,3-triazole-containing alkyl β-D-xylopyranoside surfactants.Carbohydrate research · 2013Article
- Efficient synthesis of fluorescent squaraine rotaxane dendrimers.Organic letters · 2010Article
- Modular synthesis of biologically active phosphatidic acid probes using click chemistry.Molecular bioSystems · 2009Article
- Bio-orthogonal phosphatidylserine conjugates for delivery and imaging applications.The Journal of organic chemistry · 2008Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The copper-catalyzed azide alkyne cycloaddition is employed to modify phosphatidylcholine precursors with sn-2 acyl chains containing terminal alkyne or azide groups. Although the reactions are conducted as biphasic dispersions, the yields are essentially quantitative. Bolaamphiphiles are formed by simply clicking together two phosphatidylcholine alkyne precursors to a central bisazide scaffold. The chemistry introduces polar 1,4-triazole units into the lipophilic region of the bilayer membrane, and the bolaamphiphiles do not form stable vesicles. [structure: see text].
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Registered trials
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