ArticleNucleic acids research1991
A mixed group II/group III twintron in the Euglena gracilis chloroplast ribosomal protein S3 gene: evidence for intron insertion during gene evolution.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 36 citations in OpenAlex.
- A functional twintron, 'zombie' twintrons and a hypermobile group II intron invading itself in plant mitochondria.Nucleic acids research · 2020Article
- Pervasive, Genome-Wide Transcription in the Organelle Genomes of Diverse Plastid-Bearing Protists.G3 (Bethesda, Md.) · 2017Article
- Review
- Evolution of group II introns.Mobile DNA · 2015Article
- Molecular evolution of the mtDNA encoded rps3 gene among filamentous ascomycetes fungi with an emphasis on the Ophiostomatoid fungi.Journal of molecular evolution · 2009Article
- Lateral transfer of introns in the cryptophyte plastid genome.Nucleic acids research · 2008Article
- Evidence for the late origin of introns in chloroplast genes from an evolutionary analysis of the genus Euglena.Nucleic acids research · 1995Article
- Chloroplast ribosomes and protein synthesis.Microbiological reviews · 1994Review
- A group III twintron encoding a maturase-like gene excises through lariat intermediates.Nucleic acids research · 1994Article
- Complete sequence of Euglena gracilis chloroplast DNA.Nucleic acids research · 1993Article
- A complex twintron is excised as four individual introns.Nucleic acids research · 1993Article
- A novel Euglena gracilis chloroplast operon encoding four ATP synthase subunits and two ribosomal proteins contains 17 introns.Current genetics · 1993Article
- Chloroplast group III twintron excision utilizing multiple 5'- and 3'-splice sites.The EMBO journal · 1992Article
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3 authors at 1 institution in 1 country.
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Abstract
The splicing of a 409 nucleotide intron from the Euglena gracilis chloroplast ribosomal protein S3 gene (rps3) was examined by cDNA cloning and sequencing, and northern hybridization. Based on the characterization of a partially spliced pre-mRNA, the intron was characterized as a 'mixed' twintron, composed of a 311 nucleotide group II intron internal to a 98 nucleotide group III intron. Twintron excision is via a 2-step sequential splicing pathway, with removal of the internal group II intron preceding excision of the external group III intron. Based on secondary structural analysis of the twintron, we propose that group III introns may represent highly degenerate versions of group II introns. The existence of twintrons is interpreted as evidence that group II introns were inserted during the evolution of Euglena chloroplast genes from a common ancestor with eubacteria, archaebacteria, cyanobacteria, and other chloroplasts.
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