ArticleJournal of chemical ecology2007
Allelochemical induction of cytochrome P450 monooxygenases and amelioration of xenobiotic toxicity in Helicoverpa zea.
Article in Journal of chemical ecology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- Physiological and Biochemical Mechanisms ofInsects · 2025Article
- Review of Allelopathy in Green Tides: The Case ofBiology · 2024Review
- Effects of Honeysuckle Varieties on Protective and Detoxifying Enzyme Activities in Heterolocha Jinyinhuaphaga Chu (Lepidoptera: Geometridae) Larvae.Journal of chemical ecology · 2023Article
- Metabolic-based insecticide resistance mechanism and ecofriendly approaches for controlling of beet armyworm Spodoptera exigua: a review.Environmental science and pollution research international · 2022Review
- Effects of phytocompound Precocene 1 on the expression and functionality of the P450 gene in λ-cyhalothrin-resistantFrontiers in physiology · 2022Article
- Toxicity of Bioactive Molecule Andrographolide againstMolecules (Basel, Switzerland) · 2021Article
- Exposure ofInsects · 2021Article
- Identification of Wild-TypeInsects · 2021Article
- Transcriptome analysis of a social caterpillar, Drepana arcuata: De novo assembly, functional annotation and developmental analysis.PloS one · 2020Article
- Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides.BMC genomics · 2019Article
- Aflatoxin BToxins · 2019Article
- Influence of Neighboring Clonal-Colonies on Aflatoxin Production byFrontiers in microbiology · 2019Article
- Identification of Two Cytochrome Monooxygenase P450 Genes, CYP321A7 and CYP321A9, from the Tobacco Cutworm Moth (Spodoptera Litura) and Their Expression in Response to Plant Allelochemicals.International journal of molecular sciences · 2017Article
- The Enterobacterium Trabulsiella odontotermitis Presents Novel Adaptations Related to Its Association with Fungus-Growing Termites.Applied and environmental microbiology · 2015Article
- Expression analysis of two P450 monooxygenase genes of the tobacco cutworm moth (Spodoptera litura) at different developmental stages and in response to plant allelochemicals.Journal of chemical ecology · 2015Article
- Common and unique cis-acting elements mediate xanthotoxin and flavone induction of the generalist P450 CYP321A1.Scientific reports · 2014Article
- Larval Helicoverpa zea Transcriptional, Growth and Behavioral Responses to Nicotine and Nicotiana tabacum.Insects · 2014Article
- Article
- A link between host plant adaptation and pesticide resistance in the polyphagous spider mite Tetranychus urticae.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Polyphagous herbivores encounter allelochemicals as complex mixtures in their host plants, and the toxicity of an individual compound may be influenced by the chemical matrix in which it is encountered. Certain plant constituents may reduce toxicity of cooccurring compounds by inducing detoxification systems, including cytochrome P450s, which can metabolize a broad range of substances. The polyphagous corn earworm Helicoverpa zea encounters a diversity of plant allelochemicals in its many host plants and, as well, can encounter aflatoxins, mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus that infect damaged grains. Dietary supplementation of each of three plant allelochemicals that are frequently (coumarin, COU), occasionally (indole-3-carbinol, 13C), or rarely (xanthotoxin, XAN) encountered by H. zea larvae substantially reduced the toxicity of aflatoxin B1 (AFB1) to H. zea. Compared to fourth instars on diets containing 1 microg/g AFB1 that failed to develop and pupate, fourth instars on diets containing I3C and XAN increased in mass by 216.1 and 700% after 6 days, and pupated at rates of 40 and 88%, respectively. Diets containing COU or XAN also significantly reduced the mortality rates of caterpillars exposed to the insecticides, diazinon and carbaryl. Diets containing COU and XAN increased CYP6B8 transcripts 2.6-fold; CYP321A1 transcripts increased 20.7, 8.3, and 10.6-fold in response to COU, I3C, and XAN, respectively. These results indicate that consumption of plant allelochemicals can ameliorate toxicity of natural and synthetic toxins encountered by insects, and they suggest that P450s induced by these allelochemicals contribute to detoxification of these chemicals in H. zea.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.