ArticleVeterinary research communications2007
Experimental infection of pigs with 'Candidatus Helicobacter suis'.
Article in Veterinary research communications, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- The prevalence of porcine gastric ulcer and Helicobacter suis in Taiwan.The Journal of veterinary medical science · 2024Article
- Gastric Helicobacter species associated with dogs, cats and pigs: significance for public and animal health.Veterinary research · 2022Review
- Isolation and identification of Candida tropicalis in sows with fatal infection: a case report.BMC veterinary research · 2021Article
- Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma.Cancer medicine · 2019Article
- Helicobacter suis binding to carbohydrates on human and porcine gastric mucins and glycolipids occurs via two modes.Virulence · 2018Article
- Mucus-Pathogen Interactions in the Gastrointestinal Tract of Farmed Animals.Microorganisms · 2018Review
- Helicobacter suis induces changes in gastric inflammation and acid secretion markers in pigs of different ages.Veterinary research · 2017Article
- Attempted experimental reproduction of porcine periweaning-failure-to-thrive syndrome using tissue homogenates.PloS one · 2014Article
- The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori.Veterinary research · 2012Article
- Genome sequence of Helicobacter suis supports its role in gastric pathology.Veterinary research · 2011Article
- Detection of Helicobacter spp. in gastric, fecal and saliva samples from swine affected by gastric ulceration.Journal of veterinary science · 2010Article
- Gastric helicobacters in domestic animals and nonhuman primates and their significance for human health.Clinical microbiology reviews · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
'Candidatus Helicobacter suis' is a spiral-shaped bacterium that colonizes the stomach of more than 60% of slaughter pigs. The role of 'Candidatus Helicobacter suis' in gastric disease of pigs is still unclear. Experimental studies in pigs are lacking because this bacterium is unculturable until now. An inoculation protocol using 'Candidatus Helicobacter suis' infected mouse stomach homogenate was used to reproduce the infection in pigs. Control animals were inoculated using negative mouse stomach homogenate. Pigs were inoculated three times with one-week intervals and euthanized 6 weeks post inoculation. Tissue samples were taken from different mucosal stomach regions to detect 'Candidatus Helicobacter suis' by PCR and urease test. Mucosal inflammation was evaluated on formalin-fixed tissue samples. Lesions in the pars oesophagea were scored macroscopically. Infection was successful in all challenged animals, with the antrum and the fundus being predominantly positive. Infection was associated with infiltration of lymphocytes and plasma cells in the antral mucosa, evolving to follicular gastritis. No apparent inflammation of the fundic stomach region was detected in the infected animals. A clear link between 'Candidatus Helicobacter suis' and pars oesophageal lesions could not be found.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.