ArticlePediatric nephrology (Berlin, Germany)2007
Imaging strategies for vesicoureteral reflux diagnosis.
Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Evidence-based clinical practice guideline for management of urinary tract infection and primary vesicoureteric reflux.Pediatric nephrology (Berlin, Germany) · 2024Guideline
- Ureteric jet Doppler waveform: is it a reliable predictor of vesicoureteric reflux in children?Pediatric nephrology (Berlin, Germany) · 2009Trial
- Screening of pediatric patients with congenital anomalies of the kidney and urinary tract for associated congenital heart disease in a tertiary care setting.Pediatric nephrology (Berlin, Germany) · 2026Article
- Can diagnostic and imaging recommendations from the 2011 AAP UTI guidelines be applied to infants <2 months of age?Journal of pediatric urology · 2022Article
- Vesicoureteral refux detection in children: a comparison of the midline-to-orifice distance measurement by ultrasound and voiding urosonography.Pediatric nephrology (Berlin, Germany) · 2016Article
- Vesicoureteral reflux: current management in children.Current urology reports · 2014Review
- Comparison of procalcitonin and different guidelines for first febrile urinary tract infection in children by imaging.Pediatric nephrology (Berlin, Germany) · 2014Article
- Efficacy of magnetic resonance urography in detecting renal scars in children with vesicoureteral reflux.Pediatric nephrology (Berlin, Germany) · 2014Article
- Maximizing the sensitivity of the indirect radionuclide cystogram: a retrospective audit.Pediatric nephrology (Berlin, Germany) · 2013Article
- The accuracy and health risks of a voiding cystourethrogram after a febrile urinary tract infection.Journal of pediatric urology · 2012Article
- Catheter-free methods for vesicoureteric reflux detection: our experience and a critical appraisal of existing data.Pediatric nephrology (Berlin, Germany) · 2010Review
- Vesicoureteral reflux, a benign condition.Pediatric nephrology (Berlin, Germany) · 2009Article
- Imaging in childhood urinary tract infections: time to reduce investigations.Pediatric nephrology (Berlin, Germany) · 2008Review
- Continuing medical education: introducing four papers on vesicoureteral reflux.Pediatric nephrology (Berlin, Germany) · 2007Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of vesicoureteral reflux (VUR), although reported to be low in the general population, is high in children with urinary tract infection (UTI), first degree relatives of patients with known VUR and children with antenatal hydronephrosis. In addition, it has been shown that VUR and UTIs are associated with renal scarring, predisposing to serious long-term complications, i.e., hypertension, chronic renal insufficiency and complications of pregnancy. Therefore, diagnostic imaging for the detection of VUR in the high-risk groups of children has been a standard practice. However, none of these associations has been validated with controlled studies, and recently the value of identifying VUR after a symptomatic UTI has been questioned. In addition, several studies have shown that renal damage may occur in the absence of VUR. On the other hand, some patients, mainly males, may have primary renal damage, associated with high-grade VUR, without UTI. Recently, increasing skepticism has been noted concerning how and for whom it is important to investigate for VUR. It has been suggested that the absence of renal lesions after the first UTI in children may rule out VUR of clinical significance and reinforces the redundancy of invasive diagnostic techniques. Therefore, the priority of imaging strategies should focus on early identification of renal lesions to prevent further deterioration.
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