Evidence map›Paper›PMID 17215498›Full record

ArticleJournal of neurophysiology2007

Responses of the rat olfactory epithelium to retronasal air flow.

John W Scott, Humberto P Acevedo, Lisa Sherrill, Maggie Phan

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

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  8. Tuning to odor solubility and sorption pattern in olfactory epithelial responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
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  11. Retronasal odor representations in the dorsal olfactory bulb of rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John W ScottDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. JohnS@cellbio.emory.edu
Humberto P Acevedo
Lisa Sherrill
Maggie Phan
Emory University · US

Funding

PHYSIOLOGICAL ANALYSIS OF THE OLFACTORY PROJECTIONSR01DC000113 · NIDCD · EMORY UNIVERSITY · PI SCOTT, JOHN W · 1989 to 2006
$2.0M
PSYCHOPHYSICAL MODELING IN BINAURAL HEARINGF32DC000113 · NIDCD · UNIVERSITY OF FLORIDA · PI SABERI, KOUROSH · 1994 to 1996
–
NIDCD NIH HHS DC-00113NIDCD NIH HHS F32 DC000113NIDCD NIH HHS R01 DC000113
6 · The paper itself

Abstract

Responses of the rat olfactory epithelium were assessed with the electroolfactogram while odorants were presented to the external nares with an artificial sniff or to the internal nares by positive pressure. A series of seven odorants that varied from very polar, hydrophilic odorants to very nonpolar, hydrophobic odorants were used. Although the polar odorants activated the dorsal olfactory epithelium when presented by the external nares (orthonasal presentation), they were not effective when forced through the nasal cavity from the internal nares (retronasal presentation). However, the nonpolar odorants were effective in both stimulus modes. These results were independent of stimulus concentration or of humidity of the carrier air. Similar results were obtained with multiunit recordings from olfactory bulb. These results help to explain why human investigations often report differences in the sensation or ability to discriminate odorants presented orthonasally versus retronasally. The results also strongly support the importance of odorant sorption in normal olfactory processes.

Indexed as

OdorantsAction PotentialsAnimalsHumidityMaleMouthNasal CavityOlfactory MucosaRatsRats, Sprague-DawleySmellStimulation, Chemical

Identifiers

PMID17215498
PMCPMC2225990
OpenAlexW1990208776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.