Evidence map›Paper›PMID 17213414›Full record

ArticleAJNR. American journal of neuroradiology2007

Angiography of primary central nervous system angiitis of childhood: conventional angiography versus magnetic resonance angiography at presentation.

R I Aviv, S M Benseler, G DeVeber, E D Silverman, P N Tyrrell, L M Tsang, D Armstrong

Open access · greenAbstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Diagnosis and Treatment of Primary Central Nervous System Angiitis.Current treatment options in neurology · 2018
    Review
  6. Article
  7. Primary angiitis of the central nervous system in a 7-month-old infant.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Article
  8. Review
  9. Article
  10. Article
  11. The spectrum of CNS vasculitis in children and adults.Nature reviews. Rheumatology · 2011
    Review
  12. Cerebral aneurysms in children: are we talking about a single pathological entity?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010
    Article
  13. Review
  14. Unusual cause of acute neurologic deficit in childhood: primary central nervous system vasculitis presenting with basilar arterial occlusion.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2009
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R I AvivDivision of Neuroradiology, Hospital for Sick Children, Toronto, Ontario, Canada. richardaviv@lineone.net
S M Benseler
G DeVeber
E D Silverman
P N Tyrrell
L M Tsang
D Armstrong
Hospital for Sick Children · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTo systematically analyze conventional angiographic (CA) features of children with primary central nervous system angiitis (cPACNS), to compare and correlate CA and MR angiography (MRA) lesion characteristics, and to define the sensitivity and specificity of MRA with CA as a reference standard.

methodsA retrospective, single-center cohort study of consecutive patients with cPACNS was performed. Patients with CA and MRA studies at diagnosis were included. Imaging studies were blindly reviewed by 2 neuroradiologists using a standard analysis protocol. CA and MRA studies were compared using nonparametric analysis.

resultsOf 45 patients with MRA at diagnosis, there were 25 for whom CA and MRA studies were performed within 1 month of each other. These comprised the study group. The CA distribution of lesions was multifocal (76%) and proximal (86%) (P < .05) with a trend toward unilaterality (P = .06) with anterior circulation involvement (P = .08). The sensitivity and specificity of MRA for CA abnormality was 70% and 98%, respectively. There was no significant difference between MRA and CA for lesion detection or characterization (P = .87), and the modalities showed a fair correlation (kappa = 0.4).

conclusionAngiographic lesions are multifocal and occur proximally and unilaterally within the anterior circulation. There is no significant difference in the ability of MRA to detect and characterize lesions when compared with CA.

Indexed as

Cerebral AngiographyImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyAdolescentCerebral ArteriesChildChild, PreschoolCohort StudiesConstriction, PathologicFemaleHumansInfantMaleSensitivity and SpecificityStatistics as Topic

Identifiers

PMID17213414
PMCPMC8134080
OpenAlexW1866487554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.