Evidence map›Paper›PMID 17209016›Full record

ArticleJournal of bacteriology2007

Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.

Athanasios Lykidis, Konstantinos Mavromatis, Natalia Ivanova, Iain Anderson, Miriam Land, Genevieve DiBartolo, Michele Martinez, Alla Lapidus, Susan Lucas, Alex Copeland and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 208 citations in OpenAlex.

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  8. A thermostable and CBM2-linked GH10 xylanase fromFrontiers in bioengineering and biotechnology · 2022
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Athanasios LykidisDepartment of Energy, Joint Genome Institute, 2800 Mitchell Dr., Walnut Creek, CA 94598, USA. alykidis@lbl.gov
Konstantinos Mavromatis
Natalia Ivanova
Iain Anderson
Miriam Land
Genevieve DiBartolo
Michele Martinez
Alla Lapidus
Susan Lucas
Alex Copeland
Paul Richardson
David B Wilson
Nikos Kyrpides
Joint Genome Institute · USCornell University · USOak Ridge National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thermobifida fusca is a moderately thermophilic soil bacterium that belongs to Actinobacteria. It is a major degrader of plant cell walls and has been used as a model organism for the study of secreted, thermostable cellulases. The complete genome sequence showed that T. fusca has a single circular chromosome of 3,642,249 bp predicted to encode 3,117 proteins and 65 RNA species with a coding density of 85%. Genome analysis revealed the existence of 29 putative glycoside hydrolases in addition to the previously identified cellulases and xylanases. The glycosyl hydrolases include enzymes predicted to exhibit mainly dextran/starch- and xylan-degrading functions. T. fusca possesses two protein secretion systems: the sec general secretion system and the twin-arginine translocation system. Several of the secreted cellulases have sequence signatures indicating their secretion may be mediated by the twin-arginine translocation system. T. fusca has extensive transport systems for import of carbohydrates coupled to transcriptional regulators controlling the expression of the transporters and glycosylhydrolases. In addition to providing an overview of the physiology of a soil actinomycete, this study presents insights on the transcriptional regulation and secretion of cellulases which may facilitate the industrial exploitation of these systems.

Indexed as

Genome, BacterialSequence Analysis, DNASoil MicrobiologyActinomycetalesBacterial ProteinsCellulasesCelluloseGene Expression Regulation, BacterialGenomicsMolecular Sequence DataBacterial ProteinsCellulasesCellulose

Identifiers

PMID17209016
PMCPMC1899369
OpenAlexW2115326165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.