ArticleSchizophrenia research2007
Phenylthiocarbamide (PTC) perception in patients with schizophrenia and first-degree family members: relationship to clinical symptomatology and psychophysical olfactory performance.
Article in Schizophrenia research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Phenome-wide investigation of dietary and health outcomes associated with bitter taste receptor gene TAS2R38.European journal of nutrition · 2025Article
- The COVID-19 and Taste Lab: A Mini Course-Based Undergraduate Research Experience on Taste Differences and COVID-19 Susceptibility.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2023Article
- Article
- The influence of TAS2R38 bitter taste gene polymorphisms on obesity risk in three racially diverse groups.BioMedicine · 2021Article
- TAS2R38 bitter taste receptor and attainment of exceptional longevity.Scientific reports · 2019Article
- Brain-based ranking of cognitive domains to predict schizophrenia.Human brain mapping · 2019Article
- Emotional stability is associated with the MAOA promoter uVNTR polymorphism in women.Brain and behavior · 2019Article
- Understanding the impact of taste changes in oncology care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Review
- An examination of associations between the inability to taste phenylthiocarbamide (PTC) and clinical characteristics and trait markers in first-episode, nonaffective psychotic disorders.Psychiatry research · 2013Article
- Gene set enrichment analysis of RNA-Seq data: integrating differential expression and splicing.BMC bioinformatics · 2013Article
- Phenylthiocarbamide (PTC) perception in ultra-high risk for psychosis participants who develop schizophrenia: testing the evidence for an endophenotypic marker.Psychiatry research · 2012Article
- Neuroleptic-induced parkinsonism is associated with olfactory dysfunction.Journal of neurology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The inability to taste phenylthiocarbamide (PTC; "taste-blindness") has been associated with a number of medical and neurological illnesses not typically related to taste. We examined PTC sensitivity in 67 schizophrenia patients, 30 healthy controls, and 30 first-degree relatives to determine whether taster status could represent a simple vulnerability marker. A higher prevalence of non-tasters was seen in patients and family members relative to healthy controls. Among patients, non-tasters exhibited increased levels of negative and first-rank symptoms as well as poorer right nostril odor identification skills relative to PTC tasters. These differences were not explained by age, sex, education, smoking, or intensity differences. Phenotypic variation in PTC sensitivity is thought to be genetic in origin and suggests greater illness risk for those subjects with recessive taster alleles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.