ArticleProceedings of the National Academy of Sciences of the United States of America1991
Detection of homeobox genes in development and evolution.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 167 citations in OpenAlex.
- Patterns of Conservation and Loss of Hox Genes in Xenacoelomorph Lineage Since Divergence From Last Common Bilaterian Ancestor.Genome biology and evolution · 2026Article
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- A new paradigm for animal symmetry.Interface focus · 2015Review
- Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.PloS one · 2012Article
- Expression of Hox genes during the larval development of the snail, Gibbula varia (L.)-further evidence of non-colinearity in molluscs.Development genes and evolution · 2010Article
- Conservation of ParaHox genes' function in patterning of the digestive tract of the marine gastropod Gibbula varia.BMC developmental biology · 2010Article
- Are Hox genes ancestrally involved in axial patterning? Evidence from the hydrozoan Clytia hemisphaerica (Cnidaria).PloS one · 2009Article
- Article
- NK homeobox genes with choanocyte-specific expression in homoscleromorph sponges.Development genes and evolution · 2008Article
- Changing hydrozoan bauplans by silencing Hox-like genes.PloS one · 2007Article
- Pre-bilaterian origins of the Hox cluster and the Hox code: evidence from the sea anemone, Nematostella vectensis.PloS one · 2007Article
- The existence of all three ParaHox genes in the clitellate annelid, Perionyx excavatus.Development genes and evolution · 2006Article
- Hox genes from the earthworm Perionyx excavatus.Development genes and evolution · 2003Article
- HOX genes in the sepiolid squid Euprymna scolopes: implications for the evolution of complex body plans.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Evolution of Antp-class genes and differential expression of Hydra Hox/paraHox genes in anterior patterning.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- A genetic screen for zygotic embryonic lethal mutations affecting cuticular morphology in the wasp Nasonia vitripennis.Genetics · 2000Article
- Homeobox genes in the ribbonworm Lineus sanguineus: evolutionary implications.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Genetic redundancy caused by gene duplications and its evolution in networks of transcriptional regulators.Biological cybernetics · 1996Article
- Expression of PTPH1, a rat protein tyrosine phosphatase, is restricted to the derivatives of a specific diencephalic segment.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Identification of planarian homeobox sequences indicates the antiquity of most Hox/homeotic gene subclasses.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The homeobox genes encode a family of DNA-binding regulatory proteins whose function and genomic organization make them an important model system for the study of development and differentiation. Oligonucleotide primers corresponding to highly conserved regions of Antennapediaclass homeodomains were designed to detect and identify homeobox sequences in populations of DNA or RNA by means of the polymerase chain reaction (PCR). Here we present a survey of sequences detected by PCR using an initial set of primers (HoxA and HoxB) based on an early nucleotide consensus for vertebrate Antennapedia-class homeodomains. Several novel sequences are reported from both mouse genomic DNA and RNA from the developing mouse telencephalon. Forebrain-derived clones are similar to the chicken CHox7, Drosophila H2.0, and mouse Hlx genes. PCR also proved to be a rapid method for identifying homeobox sequences from diverse metazoan species. Cloning of three Antennapedia-related sequences from cnidarians provides evidence of ancient roles for homeobox genes early in metazoan evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.