ReviewProceedings of the American Thoracic Society2007
Human and murine obliterative bronchiolitis in transplant.
Review in Proceedings of the American Thoracic Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 54 citations in OpenAlex.
- Cross-Regulation of F-Box Protein FBXL2 with T-bet and TNF-α during Acute and Chronic Lung Allograft Rejection.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome.International journal of molecular sciences · 2020Article
- LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats.Journal of cardiothoracic surgery · 2017Article
- Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017Article
- Rapamycin prevents bronchiolitis obliterans through increasing infiltration of regulatory B cells in a murine tracheal transplantation model.The Journal of thoracic and cardiovascular surgery · 2016Article
- Revascularization of the graft in obliterative bronchiolitis after heterotopic tracheal transplantation.Physiological reports · 2016Article
- The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model.Transplantation direct · 2015Article
- Bone marrow-derived multipotent stromal cells attenuate inflammation in obliterative airway disease in mouse tracheal allografts.Stem cells international · 2014Article
- Prevention of airway allograft tolerance by polyinosinic:polycytidylic acid requires type I interferon responsiveness for mouse airway obliteration.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2013Article
- Prevention of the second stage of epithelial loss is a potential novel treatment for bronchiolitis obliterans.The Journal of thoracic and cardiovascular surgery · 2013Article
- Rattus model utilizing selective pulmonary ischemia induces bronchiolitis obliterans organizing pneumonia.Shock (Augusta, Ga.) · 2013Article
- T regulatory cells play a significant role in modulating MHC class I antibody-induced obliterative airway disease.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012Article
- Development of obliterative bronchiolitis in a murine model of orthotopic lung transplantation.Journal of visualized experiments : JoVE · 2012Article
- Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation.Respiratory research · 2012Article
- Chronic rejection pathology after orthotopic lung transplantation in mice: the development of a murine BOS model and its drawbacks.PloS one · 2012Article
- Article
- The link between major histocompatibility complex antibodies and cell proliferation.Transplantation reviews (Orlando, Fla.) · 2011Review
- Green tea epigallo-catechin-galleate ameliorates the development of obliterative airway disease.Experimental lung research · 2011Article
- Neutralizing IL-17 prevents obliterative bronchiolitis in murine orthotopic lung transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2011Article
- Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats.PloS one · 2011Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Obliterative bronchiolitis is a devastating illness that limits the long-term success of lung transplantation. Its high prevalence and overall poor response to current therapeutic measures demands further research to elucidate pathogenic mechanisms. Toward this goal, there is a role for animal models to study the mechanisms of obliterative bronchiolitis, such as the murine heterotopic tracheal allograft model. This review compares the tracheal allograft model to human obliterative bronchiolitis pathology and highlights the important mechanisms of airway rejection described using this model. Although certain limitations exist, the pursuit of proof-of-concept studies in this model, as well as other animal models, can provide the basis for genetic and cellular translational human studies directed toward post-transplant obliterative bronchiolitis pathogenesis. To meet these challenges, we call for the establishment of a National Institutes of Health-supported Lung Transplant Network to better orchestrate translational research efforts in obliterative bronchiolitis pathogenesis and treatment, and to advance the field of lung transplantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.