ReviewThe Journal of clinical investigation2007
Celiac disease: pathogenesis of a model immunogenetic disease.
Review in The Journal of clinical investigation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 1 synthesis or guideline pooled it, 383 citations in OpenAlex.
- Risk of Celiac Disease in the First- and Second-Degree Relatives of Patients With Celiac Disease: A Systematic Review and Meta-Analysis.The American journal of gastroenterology · 2015Pooled it
- Celiac disease serology and gut microbiome following proton pump inhibitor treatment.Medicine · 2020Trial
- A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults.Nature communications · 2018Trial
- Probe-based confocal laser microscopy identifies criteria predictive of active celiac sprue.Digestive diseases and sciences · 2012Trial
- Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial.PloS one · 2011Trial
- Altered miRNA expression in duodenal tissue of celiac patients and the impact of a gluten-free diet: a preliminary study.Molecular biology reports · 2025Article
- An updated meta-analysis on the association between celiac disease and cardiovascular diseases.American journal of cardiovascular disease · 2025Review
- Co-occurrence of autoimmune diseases and metabolic disorders in familial mediterranean fever patients: review of literature and case reports.Frontiers in immunology · 2025Review
- Celiac Disease as a Genetic Predisposing Factor for Dermatitis Herpetiformis: A Two-Sample Mendelian Randomization Analysis.Clinical, cosmetic and investigational dermatology · 2025Article
- Intestinal organ chips for disease modelling and personalized medicine.Nature reviews. Gastroenterology & hepatology · 2024Review
- Expression of MicroRNAs in Adults with Celiac Disease: A Narrative Review.International journal of molecular sciences · 2024Review
- Translation of cell therapies to treat autoimmune disorders.Advanced drug delivery reviews · 2024Review
- Expression of Elafin and CD200 as Immune Checkpoint Molecules Involved in Celiac Disease.International journal of molecular sciences · 2024Article
- Assessment of Novel Proteins Triggering Celiac Disease via Docking-Based Approach.Molecules (Basel, Switzerland) · 2023Article
- Beyond the Gut: A Systematic Review of Oral Manifestations in Celiac Disease.Journal of clinical medicine · 2023Review
- Article
- New Developments in Celiac Disease Treatment.International journal of molecular sciences · 2023Review
- Study on the in vitro digestion process of green wheat protein: Structure characterization and product analysis.Food science & nutrition · 2022Article
- Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease.Nature communications · 2022Article
- Biomarkers to Monitor Adherence to Gluten-Free Diet by Celiac Disease Patients: Gluten Immunogenic Peptides and Urinary miRNAs.Foods (Basel, Switzerland) · 2022Review
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease is characterized by small-intestinal mucosal injury and nutrient malabsorption in genetically susceptible individuals in response to the dietary ingestion of wheat gluten and similar proteins in barley and rye. Disease pathogenesis involves interactions among environmental, genetic, and immunological factors. Although celiac disease is predicted by screening studies to affect approximately 1% of the population of the United States and is seen both in children and in adults, 10%-15% or fewer of these individuals have been diagnosed and treated. This article focuses on the role of adaptive and innate immune mechanisms in the pathogenesis of celiac disease and how current concepts of immunopathogenesis might provide alternative approaches for treating celiac disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.