ArticleThe Plant cell2006
Reduction of benzenoid synthesis in petunia flowers reveals multiple pathways to benzoic acid and enhancement in auxin transport.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 180 citations in OpenAlex.
- Metabolic and molecular basis of floral scent differentiation in single- versus double-flowered tuberose (Agave amica).Plant biology (Stuttgart, Germany) · 2026Article
- Benzyl alcohol biosynthesis and its subcellular compartmentalization enable scent formation and salicylic acid production.Nature communications · 2026Article
- Study of Intact Glycosidic Aroma Precursors in Recovered Minority White Grape Varieties under Water Stress Conditions.Journal of agricultural and food chemistry · 2026Article
- Targeted Gene Modification ofInternational journal of molecular sciences · 2026Article
- Article
- The Scent of Lily Flowers: Advances in the Identification, Biosynthesis, and Regulation of Fragrance Components.International journal of molecular sciences · 2025Review
- Diatom volatile organic compound production is driven by diel metabolism and the cell cycle.Frontiers in microbiology · 2025Article
- Peroxisomal Localization of Benzyl Alcohol O-Benzoyltransferase HSR201 is Mediated by a Non-canonical Peroxisomal Targeting Signal and Required for Salicylic Acid Biosynthesis.Plant & cell physiology · 2024Article
- Floral volatile benzenoids/phenylpropanoids: biosynthetic pathway, regulation and ecological value.Horticulture research · 2024Article
- Research advances in regulation and genetic engineering of floral scents.Plant biotechnology (Tokyo, Japan) · 2024Article
- Yields and molecular composition of gas phase and secondary organic aerosol from the photooxidation of the volatile consumer product benzyl alcohol: formation of highly oxygenated and hydroxy nitroaromatic compounds.Atmospheric chemistry and physics · 2023Article
- Emission of floral volatiles is facilitated by cell-wall non-specific lipid transfer proteins.Nature communications · 2023Article
- A whiff of the future: functions of phenylalanine-derived aroma compounds and advances in their industrial production.Plant biotechnology journal · 2022Review
- A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants.Nature communications · 2022Article
- Molecular evolution and structural analyses of proteins involved in metabolic pathways of volatile organic compounds in Petunia hybrida (Solanaceae).Genetics and molecular biology · 2022Article
- Floral Scents and Fruit Aromas: Functions, Compositions, Biosynthesis, and Regulation.Frontiers in plant science · 2022Review
- Revealing floral metabolite network in tuberose that underpins scent volatiles synthesis, storage and emission.Plant molecular biology · 2021Article
- A peroxisomal β-oxidative pathway contributes to the formation of C6-C1 aromatic volatiles in poplar.Plant physiology · 2021Article
- Cuticle thickness affects dynamics of volatile emission from petunia flowers.Nature chemical biology · 2021Article
- Plant Volatile Organic Compounds Evolution: Transcriptional Regulation, Epigenetics and Polyploidy.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, benzoic acid (BA) is believed to be synthesized from Phe through shortening of the propyl side chain by two carbons. It is hypothesized that this chain shortening occurs via either a beta-oxidative or non-beta-oxidative pathway. Previous in vivo isotope labeling and metabolic flux analysis of the benzenoid network in petunia (Petunia hybrida) flowers revealed that both pathways yield benzenoid compounds and that benzylbenzoate is an intermediate between L-Phe and BA. To test this hypothesis, we generated transgenic petunia plants in which the expression of BPBT, the gene encoding the enzyme that uses benzoyl-CoA and benzyl alcohol to make benzylbenzoate, was reduced or eliminated. Elimination of benzylbenzoate formation decreased the endogenous pool of BA and methylbenzoate emission but increased emission of benzyl alcohol and benzylaldehyde, confirming the contribution of benzylbenzoate to BA formation. Labeling experiments with 2H5-Phe revealed a dilution of isotopic abundance in most measured compounds in the dark, suggesting an alternative pathway from a precursor other than Phe, possibly phenylpyruvate. Suppression of BPBT activity also affected the overall morphology of petunia plants, resulting in larger flowers and leaves, thicker stems, and longer internodes, which was consistent with the increased auxin transport in transgenic plants. This suggests that BPBT is involved in metabolic processes in vegetative tissues as well.
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