ArticleInfectious agents and cancer2006
Evolutionarily new sequences expressed in tumors.
Article in Infectious agents and cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Review
- The Theory ofGenes · 2022Article
- Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently.Scientific reports · 2019Article
- Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans.Infectious agents and cancer · 2019Article
- Expression of evolutionarily novel genes in tumors.Infectious agents and cancer · 2016Review
- PBOV1 is a human de novo gene with tumor-specific expression that is associated with a positive clinical outcome of cancer.PloS one · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarlier we suggested the concept of the positive evolutionary role of tumors. According to this concept, tumors provide conditions for the expression of evolutionarily new and/or sleeping genes in their cells. Thus, tumors are considered as evolutionary proving ground or reservoir of expression. To support this concept we have previously characterized in silico and experimentally a new class of human tumor-related transcribed sequences.
resultsIn this article we describe results of further studies of previously described tumor-related sequences. The results of molecular phylogeny studies, Southern hybridization experiments and computational comparison with genomes of other species are presented.
conclusionThese results suggest that these previously described tumor-related human transcripts are also relatively evolutionarily new.
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Registered trials
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