ReviewMolecular cell2006
To die or not to die: a HAT trick.
Review in Molecular cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- TRIM-endous functional network of tripartite motif 29 (TRIM29) in cancer progression and beyond.Cancer metastasis reviews · 2024Review
- Build muscles and protect myelin.NeuroImmune pharmacology and therapeutics · 2024Review
- Muscle-building supplement β-hydroxy β-methylbutyrate stimulates the maturation of oligodendroglial progenitor cells to oligodendrocytes.Journal of neurochemistry · 2024Article
- KAT8, lysine acetyltransferase 8, is required for adipocyte differentiation in vitro.Biochimica et biophysica acta. Molecular basis of disease · 2021Article
- RNF8 promotes efficient DSB repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60.Cell proliferation · 2020Article
- Metformin suppresses melanoma progression by inhibiting KAT5-mediated SMAD3 acetylation, transcriptional activity and TRIB3 expression.Oncogene · 2018Article
- Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.Molecular biology of the cell · 2016Article
- Article
- RNAi screening identifies KAT8 as a key molecule important for cancer cell survival.International journal of clinical and experimental pathology · 2013Article
- An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation.PloS one · 2012Article
- Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes.PloS one · 2012Article
- Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl.Molecular cancer · 2011Article
- Steroid receptor coactivator (SRC) family: masters of systems biology.The Journal of biological chemistry · 2010Review
- Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster.Experimental gerontology · 2010Article
- Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells.Trends in biochemical sciences · 2009Review
- PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.Oncogene · 2008Article
- hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells.Journal of virology · 2008Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this issue of Molecular Cell, two manuscripts (Sykes et al., 2006) propose that the decision to undergo apoptosis upon DNA damage is mediated through acetylation of p53 within its DNA-binding domain by MYST histone acetyltransferases.
Indexed as
Identifiers
17189182What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.