ArticleLipids2006
Polyunsaturated phosphatidylinositol and diacylglycerol substantially modify the fluidity and polymorphism of biomembranes: a solid-state deuterium NMR study.
Article in Lipids, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 26 citations in OpenAlex.
- Integrated Proteomics and Metabolomics Analysis of Perirenal Adipose Tissue in Obese Rabbits Treated with a Restricted Diet.Biology · 2021Article
- Lipid species affect morphology of endoplasmic reticulum: a sea urchin oocyte model of reversible manipulation.Journal of lipid research · 2019Article
- Acute depletion of diacylglycerol from theJournal of lipid research · 2018Article
- The physical influence of inositides-a disproportionate effect?Journal of chemical biology · 2015Article
- Phospholipases may play multiple roles in anisotropic plant cell growth.Protoplasma · 2013Article
- Phosphatidylinositol induces fluid phase formation and packing defects in phosphatidylcholine model membranes.Chemistry and physics of lipids · 2012Article
- Key role of polyphosphoinositides in dynamics of fusogenic nuclear membrane vesicles.PloS one · 2011Article
- Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides.PloS one · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the main biological systems that can be used as a model for studying the molecular mechanisms involved in membrane fusion is the formation of the nuclear envelope (NE). NE assembly to form the male pronucleus at fertilization occurs by binding of NE membrane precursor vesicles to chromatin and their fusion. MV1 is an NE precursor vesicle population of low density, highly enriched in [18:0/20:4]PI. The modification of [18:0/20:4]PI to [18:0/20:4]DAG leads to NE formation, and the depletion of MV1 from the total membrane precursors results in the inhibition of NE assembly. Here we show by 2H NMR studies of various physiologically relevant model membranes made of [18:0/20:4]PI, [18:0/20:4]DAG, and saturated and unsaturated PC that membranes of composition similar to MV1 exhibit dramatically enhanced fluidity and non-lamellar structures, thus providing a possible explanation for the essential role of MV1 and the modification of PI to DAG in membrane precursor vesicles during NE assembly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.