ArticleNucleic acids research2007
Histone acetylation-independent transcription stimulation by a histone chaperone.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells.Science advances · 2024Article
- Thirty years of SET/TAF1β/I2PP2A: from the identification of the biological functions to its implications in cancer and Alzheimer's disease.Bioscience reports · 2022Review
- Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.Scientific reports · 2021Article
- Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere.The Journal of cell biology · 2019Article
- Regulation of SET Gene Expression by NFkB.Molecular neurobiology · 2017Article
- A Method for Visualization of Incoming Adenovirus Chromatin Complexes in Fixed and Living Cells.PloS one · 2015Article
- Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription.Epigenetics & chromatin · 2015Article
- LHX3 interacts with inhibitor of histone acetyltransferase complex subunits LANP and TAF-1β to modulate pituitary gene regulation.PloS one · 2013Article
- Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression.Nucleic acids research · 2011Article
- Curing HIV: Pharmacologic approaches to target HIV-1 latency.Annual review of pharmacology and toxicology · 2011Review
- Regulation of nucleolar chromatin by B23/nucleophosmin jointly depends upon its RNA binding activity and transcription factor UBF.Molecular and cellular biology · 2010Article
- Core promoter acetylation is not required for high transcription from the phosphoenolpyruvate carboxylase promoter in maize.Epigenetics & chromatin · 2009Article
- Identification of distinct SET/TAF-Ibeta domains required for core histone binding and quantitative characterisation of the interaction.BMC biochemistry · 2009Article
- Transcription regulation of the rRNA gene by a multifunctional nucleolar protein, B23/nucleophosmin, through its histone chaperone activity.Molecular and cellular biology · 2008Article
- An oncoprotein from the plant pathogen agrobacterium has histone chaperone-like activity.The Plant cell · 2007Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Histone chaperones are thought to be important for maintaining the physiological activity of histones; however, their exact roles are not fully understood. The physiological function of template activating factor (TAF)-I, one of the histone chaperones, also remains unclear; however, its biochemical properties have been well studied. By performing microarray analyses, we found that TAF-I stimulates the transcription of a sub-set of genes. The transcription of endogenous genes that was up-regulated by TAF-I was found to be additively stimulated by histone acetylation. On performing an experiment with a cell line containing a model gene integrated into the chromosome, TAF-I was found to stimulate the model gene transcription in a histone chaperone activity-dependent manner additively with histone acetylation. TAF-I bound to the core histones and remodeled the chromatin structure independent of the N-terminal histone tail and its acetylation level in vitro. These results suggest that TAF-I remodel the chromatin structure through its interaction with the core domain of the histones, including the histone fold, and this mechanism is independent of the histone acetylation status.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.