Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2007
The impact of an educational DVD on cancer patients considering participation in a phase I clinical trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Audio-visual presentation of information for informed consent for participation in clinical trials.The Cochrane database of systematic reviews · 2014Pooled it
- Pooled it
- Trial
- Effects of a brief multimedia psychoeducational intervention on the attitudes and interest of patients with cancer regarding clinical trial participation: a multicenter randomized controlled trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012Trial
- Trial
- Comparing Perceptions and Decisional Conflict Towards Participation in Cancer Clinical Trials Among African American Patients Who Have and Have Not Participated.Journal of cancer education : the official journal of the American Association for Cancer Education · 2022Article
- The effect of animated consent material on participants' willingness to enrol in a placebo-controlled surgical trial: a protocol for a randomised feasibility study.Pilot and feasibility studies · 2021Article
- Article
- A comparison of patient knowledge of clinical trials and trialist priorities.Current oncology (Toronto, Ont.) · 2013Article
- Improving awareness of cancer clinical trials among Hispanic patients and families: audience segmentation decisions for a media intervention.Journal of health communication · 2013Article
- Using animation as an information tool to advance health research literacy among minority participants.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
- A DVD program on fall prevention skills training for cancer family caregivers.Journal of cancer education : the official journal of the American Association for Cancer Education · 2012Article
- Communication and informed consent in phase 1 trials: a review of the literature from January 2005 to July 2009.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2010Review
- Patient information in radiation oncology: a cross-sectional pilot study using the EORTC QLQ-INFO26 module.Radiation oncology (London, England) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
goals of workThe quality of informed consent in phase I trials is controversial, partially due to gaps in patient understanding. We assessed an educational DVD's impact on knowledge and satisfaction in cancer patients newly referred to a phase I clinic. MATERIALS AND
methodsForty-nine patients were randomly assigned to view an educational DVD (n = 22) which explained phase I trials or a placebo DVD (n = 27). Patients completed a questionnaire assessing knowledge of phase I studies and satisfaction with the DVD. The blinded interviewing physician (n = 8) rated the patient's understanding of phase I trials. MAIN
resultsThe mean patient age was 56; 61% were male. Patients who viewed the educational DVD were less likely to believe that phase I trials determine drug efficacy (p = 0.019), more likely to know that phase I drugs have not been thoroughly studied in humans (p = 0.003), and less likely to believe that these agents have proven activity against human cancers (p = 0.008). More patients who viewed the educational DVD agreed/strongly agreed that the DVD provided useful information (p < 0.001), were confident in their knowledge of phase I trials (p = 0.031), felt aided in their decision to enter a phase I study (p = 0.011), and would have more questions for their physicians because of the DVD (p = 0.017). No statistically significant difference in physician perception of patient understanding or phase I trial accrual was observed between the educational and placebo DVD groups.
conclusionsAn educational DVD increased patient knowledge and satisfaction regarding participation in phase I clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.