ReviewArchives of disease in childhood2007
Fluid therapy for children: facts, fashions and questions.
Review in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Efficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials.Pediatric nephrology (Berlin, Germany) · 2024Pooled it
- Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children.The Cochrane database of systematic reviews · 2023Pooled it
- Maintenance intravenous fluid therapy in infants with sepsis and hyponatremia: a clinical trial.BMC pediatrics · 2024Trial
- 154 compared to 54 mmol per liter of sodium in intravenous maintenance fluid therapy for adult patients undergoing major thoracic surgery (TOPMAST): a single-center randomized controlled double-blind trial.Intensive care medicine · 2019Trial
- Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers.British journal of anaesthesia · 2017Trial
- Trial
- Pediatric perioperative fluid management.Korean journal of anesthesiology · 2023Article
- Effect of controlled hypotensive hemorrhage on plasma sodium levels in anesthetized pigs: An exploratory study.Physiological reports · 2023Article
- Perioperative water and electrolyte balance and water homeostasis regulation in children with acute surgery.Pediatric research · 2023Observational
- Review
- Current Practice of Fluid Maintenance and Replacement Therapy in Mechanically Ventilated Critically Ill Children: A European Survey.Frontiers in pediatrics · 2022Article
- Efficacy and Safety of Isotonic and Hypotonic Intravenous Maintenance Fluids in Hospitalised Children: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Children (Basel, Switzerland) · 2021Article
- Fluid Rate Is Important As Much As Fluid Tonicity: An Experimental Study.The Eurasian journal of medicine · 2021Article
- Fluid-induced harm in the hospital: look beyond volume and start considering sodium. From physiology towards recommendations for daily practice in hospitalized adults.Annals of intensive care · 2021Review
- Management of Pediatric Cannabinoid Hyperemesis Syndrome: A Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021Article
- Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population.Intensive care medicine · 2018Article
- Iatrogenic Dysnatremias in Children with Acute Gastroenteritis in High-Income Countries: A Systematic Review.Frontiers in pediatrics · 2017Article
- Perioperative fluid management and postoperative hyponatremia in children.Pediatric nephrology (Berlin, Germany) · 2016Article
- Hyponatraemia: Isotonic fluids prevent hospital-acquired hyponatraemia.Nature reviews. Nephrology · 2015Article
- Association between maintenance fluid tonicity and hospital-acquired hyponatremia.The Journal of pediatrics · 2013Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluid therapy restores circulation by expanding extracellular fluid. However, a dispute has arisen regarding the nature of intravenous therapy for acutely ill children following the development of acute hyponatraemia from overuse of hypotonic saline. The foundation on which correct maintenance fluid therapy is built is examined and the difference between maintenance fluid therapy and restoration or replenishment fluid therapy for reduction in extracellular fluid volume is delineated. Changing practices and the basic physiology of extracellular fluid are discussed. Some propose changing the definition of "maintenance therapy" and recommend isotonic saline be used as maintenance and restoration therapy in undefined amounts leading to excess intravenous sodium chloride intake. Intravenous fluid therapy for children with volume depletion should first restore extracellular volume with measured infusions of isotonic saline followed by defined, appropriate maintenance therapy to replace physiological losses according to principles established 50 years ago.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.