ArticleNucleic acids research2007
Genome-wide analyses of retrogenes derived from the human box H/ACA snoRNAs.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 63 citations in OpenAlex.
- The regulatory roles of small nucleolar RNAs within their host locus.RNA biology · 2024Review
- Analysis of Fungal Genomes Reveals Commonalities of Intron Gain or Loss and Functions in Intron-Poor Species.Molecular biology and evolution · 2021Article
- SnoRNA copy regulation affects family size, genomic location and family abundance levels.BMC genomics · 2021Article
- CoCo: RNA-seq read assignment correction for nested genes and multimapped reads.Bioinformatics (Oxford, England) · 2019Article
- Functional and Structural Characterization of FAU Gene/Protein from Marine Sponge Suberites domuncula.Marine drugs · 2015Article
- Silencing of LINE-1 retrotransposons contributes to variation in small noncoding RNA expression in human cancer cells.Oncotarget · 2014Article
- Comparative genomics of eukaryotic small nucleolar RNAs reveals deep evolutionary ancestry amidst ongoing intragenomic mobility.BMC evolutionary biology · 2012Article
- CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer.RNA biology · 2012Article
- Human box C/D snoRNA processing conservation across multiple cell types.Nucleic acids research · 2012Article
- Structural and functional characterization of ribosomal protein gene introns in sponges.PloS one · 2012Article
- SNOntology: Myriads of novel snoRNAs or just a mirage?BMC genomics · 2011Article
- From snoRNA to miRNA: Dual function regulatory non-coding RNAs.Biochimie · 2011Review
- Identification of human miRNA precursors that resemble box C/D snoRNAs.Nucleic acids research · 2011Article
- Critical association of ncRNA with introns.Nucleic acids research · 2011Article
- Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer.Molecular cancer · 2010Article
- Non-coding RNAs: a key to future personalized molecular therapy?Genome medicine · 2010Article
- Systematic identification and evolutionary features of rhesus monkey small nucleolar RNAs.BMC genomics · 2010Article
- Human miRNA precursors with box H/ACA snoRNA features.PLoS computational biology · 2009Article
- Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs.BMC genomics · 2009Article
- Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites.BMC genomics · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The family of box H/ACA snoRNA is an abundant class of non-protein-coding RNAs, which play important roles in the post-transcriptional modification of rRNAs and snRNAs. Here we report the characterization in the human genome of 202 sequences derived from box H/ACA snoRNAs. Most of them were retrogenes formed using the L1 integration machinery. About 96% of the box H/ACA RNA-related sequences are found in corresponding locations on the chimpanzee and human chromosomes, while the mouse shares approximately 50% of these human sequences, suggesting that some of the H/ACA RNA-related sequences in primate occurred after the rodent/primate divergence. Of the H/ACA RNA-related sequences, 49% are found in intronic regions of protein-coding genes and 64 H/ACA-related sequences can be folded to the typical secondary structure of the box H/ACA snoRNA family, while 30 of them were recognized as functional homologs of their corresponding box H/ACA snoRNAs previously reported. Of the 64 sequences with the typical secondary structure of the box H/ACA RNA family, 11 were found in EST databases and 5 among which were shown to be expressed in more than one human tissue. Notably, U107f is nested in an intron of a protein gene coding for nudix-type motif 13, but expressed from the opposite strand, and the searching of EST databases revealed it can be expressed in liver and spleen, even in melanotic melanoma.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.