SynthesisDrug and alcohol dependence2007
Non-injection drug use and Hepatitis C Virus: a systematic review.
Synthesis in Drug and alcohol dependence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The utilization and delivery of safer smoking practices and services: a narrative synthesis of the literature.Harm reduction journal · 2023Pooled it
- APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing.Hepatology international · 2016Guideline
- Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis.Parkinsonism & related disorders · 2011Pooled it
- A meta-analysis of the hepatitis C virus distribution in diverse racial/ethnic drug injector groups.Social science & medicine (1982) · 2009Pooled it
- Meta-regression of hepatitis C virus infection in relation to time since onset of illicit drug injection: the influence of time and place.American journal of epidemiology · 2008Pooled it
- The HCV Synthesis Project: scope, methodology, and preliminary results.BMC medical research methodology · 2008Pooled it
- Prevalence and Phylogenetic Characterization of Hepatitis C Virus Among Indian Men Who Have Sex With Men: Limited Evidence for Sexual Transmission.The Journal of infectious diseases · 2020Trial
- Bundling Rapid Human Immunodeficiency Virus and Hepatitis C Virus Testing to Increase Receipt of Test Results: A Randomized Trial.Medical care · 2020Trial
- Trial
- Characterizing and improving HIV and hepatitis knowledge among primary prescription opioid abusers.Drug and alcohol dependence · 2013Trial
- A comparison among tapentadol tamper-resistant formulations (TRF) and OxyContin® (non-TRF) in prescription opioid abusers.Addiction (Abingdon, England) · 2013Trial
- A trial to reduce hepatitis C seroincidence in drug users.Journal of addictive diseases · 2009Trial
- Global burden of liver cancer from 1990 to 2021 and 20-year projections: findings from the global burden of disease study 2021.International journal of surgery (London, England) · 2026Article
- Genetic Characterization of Hepatitis C Virus Among People Who Use Crack Cocaine: A Study Conducted on the Brazilian Amazon Coast.Pathogens (Basel, Switzerland) · 2025Article
- Primary Care Patient and Clinician Perspectives on Safer Use Strategies for Opioids and/or Stimulants: A Mixed-Method Study.Journal of general internal medicine · 2025Article
- "From an HCV and HIV point of view, it's been remarkable": A qualitative study about using prescribed safer supply to support people who use drugs along the HIV and HCV prevention and treatment cascades in Ontario, Canada.Journal of the International AIDS Society · 2025Article
- Burden and trends of drug use disorders in young adults: global insights from GBD 2021.Frontiers in psychiatry · 2025Article
- Association between non-injection drug use and hepatitis C infection among HIV-negative men who have sex with men.BMC infectious diseases · 2024Article
- Is drug use associated with the presence of periodontitis and oral lesions? A meta-analysis.Journal of periodontal & implant science · 2024Article
- Safe inhalation pipe provision (SIPP): protocol for a mixed-method evaluation of an intervention to improve health outcomes and service engagement among people who use crack cocaine in England.Harm reduction journal · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This systematic review examined the evidence on the prevalence of the Hepatitis C Virus (HCV) in non-injecting drug users (NIDUs) who sniff, smoke or snort drugs such as heroin, cocaine, crack or methamphetamine. The search included studies published from January 1989 to January 2006. Twenty-eight eligible studies were identified and the prevalence of HCV in these NIDU populations ranged from 2.3 to 35.3%. There was substantial variation in study focus and in the quality of the NIDU data presented in the studies. The results of our systematic review suggested that there are important gaps in the research of HCV in NIDUs. We identified a problem of study focus; much of the research did not aim to study HCV in users of non-injection drugs. Instead, NIDUs were typically included as a secondary research concern, with a principal focus on the problem of transmission of HCV in IDU populations. Despite methodological issues, HCV prevalence in this population is much higher than in a non-drug using population, even though some IDUs might have inadvertently been included in the NIDU samples. These studies point to a real problem of HCV in NIDU populations, but the causal pathway to infection remains unclear.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.