ReviewCurrent opinion in cell biology2007
Rehabilitation and the single cell.
Review in Current opinion in cell biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Physical Forces in Regeneration of Cells and Tissues.Cold Spring Harbor perspectives in biology · 2025Review
- Membrane Tension Regulation is Required for Wound Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Two Septin complexes mediate actin dynamics during cell wound repair.Cell reports · 2024Article
- Wound Repair of the Cell Membrane: Lessons fromCells · 2024Review
- Two Septin Complexes Mediate Actin Dynamics During Cell Wound Repair.bioRxiv : the preprint server for biology · 2023Article
- Microfluidic guillotine reveals multiple timescales and mechanical modes of wound response in Stentor coeruleus.BMC biology · 2021Article
- Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair.PLoS genetics · 2020Article
- Into the breach: how cells cope with wounds.Open biology · 2018Review
- Cellular mechanisms and signals that coordinate plasma membrane repair.Cellular and molecular life sciences : CMLS · 2018Review
- Structure and Function of an Actin-Based Filter in the Proximal Axon.Cell reports · 2017Article
- Microfluidic guillotine for single-cell wound repair studies.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Mechanics of epithelial tissues during gap closure.Current opinion in cell biology · 2016Review
- The early wound signals.Current opinion in genetics & development · 2016Review
- Cell healing: Calcium, repair and regeneration.Seminars in cell & developmental biology · 2015Review
- Mechanisms of epithelial wound detection.Trends in cell biology · 2015Review
- Rho family GTPases bring a familiar ring to cell wound repair.Small GTPases · 2015Article
- Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds.The Journal of cell biology · 2013Article
- A Rho GTPase signal treadmill backs a contractile array.Developmental cell · 2012Article
- Cytoskeleton responses in wound repair.Cellular and molecular life sciences : CMLS · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cellular damage triggers rapid resealing of the plasma membrane and repair of the cortical cytoskeleton. Plasma membrane resealing results from calcium-dependent fusion of membranous organelles and the plasma membrane at the site of the damage. Cortical cytoskeletal repair results from local assembly of actin filaments (F-actin), myosin-2 and microtubules into an array that closes around the original wound site. Control of the cytoskeletal response is exerted by local activation of the small GTPases, Rho and Cdc42. Recent work has given insight into both the membrane fusion and cytoskeletal responses to plasma membrane damage and we propose that Rho GTPase activation results at least in part from the events that drive membrane repair.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.