Evidence map›Paper›PMID 17172877›Full record

ReviewRNA biology2006

K-turn motifs in spatial RNA coding.

Henri Tiedge

Abstract readReview
In one paragraph

Review in RNA biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Identifying and searching for conserved RNA localisation signals.Methods in molecular biology (Clifton, N.J.) · 2011
    Article
  10. Review
  11. Article
  12. Article
  13. Non-protein coding RNA biomarkers and differential expression in cancers: a review.Journal of experimental & clinical cancer research : CR · 2008
    Review
  14. Article
  15. Dendritic BC200 RNA in aging and in Alzheimer's disease.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article
  16. Spatial codes in dendritic BC1 RNA.The Journal of cell biology · 2006
    Article
  17. Review
  18. Recognition of S-adenosylmethionine by riboswitches.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Henri TiedgeThe Robert F. Furchgott Center for Neural and Behavioral Science, Department of Physiology and Pharmacology, State University of New York, Health Science Center at Brooklyn, Brooklyn, New York 11203, USA. htiedge@downstate.edu

Funding

Translational Control in NeuronsR01NS046769 · NINDS · SUNY DOWNSTATE MEDICAL CENTER · PI TIEDGE, HENRI · 2003 to 2019
$4.8M
Women's Health Research: from Molecules to TherapiesK12HD043428 · NICHD · SUNY DOWNSTATE MEDICAL CENTER · PI LAROSA, JOHN · 2002 to 2006
$2.5M
NICHD NIH HHS HD043428NICHD NIH HHS K12 HD043428NINDS NIH HHS NS046769NINDS NIH HHS R01 NS046769
6 · The paper itself

Abstract

Three-dimensional architectural motifs are increasingly recognized as determinants of RNA functionality. We submit that such motifs can encode spatial information. RNAs are targeted to subcellular localities in many eukaryotic cell types, and especially in neuronal and glial cells, RNAs can be transported over long distances to their final destination sites. Such RNAs contain cis-acting long-range targeting elements, and recent evidence suggests that kink-turn motifs within such elements may act as spatial codes to direct transport. Kink-turns are complex RNA motifs that feature double- and single-stranded components and introduce a signature three-dimensional structure into helical stems. We propose that the overall architectural design as well as the individual character--as specified by nucleotide identity and arrangement--of kink-turn motifs can serve as RNA targeting determinants.

Indexed as

Nucleic Acid ConformationAnimalsBase SequenceHumansMolecular Sequence DataOpen Reading FramesRNARNA

Identifiers

PMID17172877
PMCPMC1847339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.