Evidence map›Paper›PMID 17170580›Full record

ArticleThe Korean journal of parasitology2006

Hydrogenosomal activity of Trichomonas vaginalis cultivated under different iron conditions.

Yong-Seok Kim, Hyun-Ouk Song, Ik-Hwa Choi, Soon-Jung Park, Jae-Sook Ryu

Open access · bronzeAbstract read
In one paragraph

Article in The Korean journal of parasitology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yong-Seok KimDepartment of Biochemistry and Molecular Biology, Hanyang University College of Medicine, Seoul, Korea.
Hyun-Ouk Song
Ik-Hwa Choi
Soon-Jung Park
Jae-Sook Ryu
Hanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate whether iron concentration in TYM medium influence on hydrogenosomal enzyme gene expression and hydrogenosomal membrane potential of Trichomonas vaginalis, trophozoites were cultivated in irondepleted, normal and iron-supplemented TYM media. The mRNA of hydrogenosomal enzymes, such as pyruvate ferredoxin oxidoreductase (PFOR), hydrogenase, ferredoxin and malic enzyme, was increased with iron concentrations in T. vaginalis culture media, measured by RT-PCR. Hydrogenosomal membrane potentials measured with DiOC6 also showed similar tendency, e.g. T. vaginalis cultivated in iron-depleted and iron-supplemented media for 3 days showed a significantly reduced and enhanced hydrogenosomal membrane potential compared with that of normal TYM media, respectively. Therefore, it is suggested that iron may regulate hydrogenosomal activity through hydrogenosomal enzyme expression and hydrogenosomal membrane potential.

Indexed as

Gene Expression RegulationAnimalsCulture MediaFerredoxinsGene Expression Regulation, EnzymologicHumansHydrogenHydrogenaseIronMalate DehydrogenaseMembrane PotentialsOrganellesPyruvate SynthaseReverse Transcriptase Polymerase Chain ReactionTrichomonas vaginalisCulture MediaFerredoxinsHydrogenHydrogenaseIronMalate DehydrogenasePyruvate Synthase

Identifiers

PMID17170580
PMCPMC2559125
OpenAlexW2023123540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.