Trial reportThe Journal of physiology2007
Spinal use-dependent plasticity of synaptic transmission in humans after a single cycling session.
Trial report in The Journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 82 citations in OpenAlex.
- Short-term plasticity of human spinal inhibitory circuits after isometric and isotonic ankle training.European journal of applied physiology · 2013Trial
- Focal Task-Specific Dystonia Beyond M1: Network Adaptations and a Causal-Architecture Taxonomy of Dystonia.Brain sciences · 2026Article
- Homosynaptic Depression of the Soleus Predicts Post-Stroke Gait Speed.Restorative neurology and neuroscience · 2026Article
- Effects of different fabrics on the Hoffmann reflex during local heat exposure.Journal of physical therapy science · 2024Article
- Spinal cord H-reflex post-activation depression is linked with hand motor control in adults with cerebral palsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- Temporal Profile of Descending Cortical Modulation of Spinal Excitability: Group and Individual-Specific Effects.Frontiers in integrative neuroscience · 2021Article
- Endurance Trained Athletes Do NotFrontiers in physiology · 2021Article
- Exploiting cervicolumbar connections enhances short-term spinal cord plasticity induced by rhythmic movement.Experimental brain research · 2019Article
- Plasticity Induced in the Human Spinal Cord by Focal Muscle Vibration.Frontiers in neurology · 2018Article
- Article
- How plastic are human spinal cord motor circuitries?Experimental brain research · 2017Review
- Postactivation depression of soleus H-reflex increase with recovery of lower extremities motor functions in patients with subacute stroke.Journal of physical therapy science · 2017Article
- The Complexity of H-wave Amplitude Fluctuations and Their Bilateral Cross-Covariance Are Modified According to the Previous Fitness History of Young Subjects under Track Training.Frontiers in human neuroscience · 2017Article
- Efficacy of QuadroPulse rTMS for improving motor function after spinal cord injury: Three case studies.The journal of spinal cord medicine · 2016Article
- Clinical uses of H reflexes of upper and lower limb muscles.Clinical neurophysiology practice · 2016Review
- Simultaneous Brain-Cervical Cord fMRI Reveals Intrinsic Spinal Cord Plasticity during Motor Sequence Learning.PLoS biology · 2015Article
- Slope walking causes short-term changes in soleus H-reflex excitability.Physiological reports · 2015Article
- Changes in the Spinal Neural Circuits are Dependent on the Movement Speed of the Visuomotor Task.Frontiers in human neuroscience · 2015Article
- The effect of age on post-activation depression of the upper limb H-reflex.European journal of applied physiology · 2014Article
- Pathophysiology of spasticity: implications for neurorehabilitation.BioMed research international · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
Abstract
The spinal cord is able to express use-dependent plasticity, as demonstrated in spinalized cats following treadmill training. In humans, spinal use-dependent plasticity is inferred from modifications in the size of H reflex, which are often more prominent after skilled motor training. Plasticity can develop at synaptic connections between afferent fibres and/or descending tracts and motoneurones or interneurones interposed in the spinal pathways. Here we explore whether skilled training induces a change in synaptic efficacy at the synapse between Ia afferents and soleus (Sol) motoneurones. Synaptic efficacy can be modulated presynaptically through changes of the probability of transmitter release (homosynaptic depression, HD). The frequency-related depression of the Sol H reflex, thought to reflect HD, was tested at rest, before and after one single skilled (14 subjects) or non-skilled (9 subjects) cycling training session. Performance improved in both groups but to a larger extent with skilled training, while HD increased immediately after and the day following skilled training in the absence of changes with non-skilled training. These results support the view that spinal cord function is able to encode a local motor memory.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.