Evidence map›Paper›PMID 17169152›Full record

ArticleJournal of nanobiotechnology2006

C60-fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects.

Nicole Levi, Roy R Hantgan, Mark O Lively, David L Carroll, Gaddamanugu L Prasad

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Article
  3. Silent Death by Sound: CInternational journal of molecular sciences · 2023
    Article
  4. Carbon Nanostructures, Nanolayers, and Their Composites.Nanomaterials (Basel, Switzerland) · 2021
    Review
  5. Article
  6. Mechano-signalling, induced by fullerene CInternational journal of nanomedicine · 2019
    Article
  7. Article
  8. CNanoscale research letters · 2018
    Article
  9. Fullerene CNanoscale research letters · 2017
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Nanotoxicology and nanoparticle safety in biomedical designs.International journal of nanomedicine · 2011
    Review
  15. Article
  16. Review
  17. Article
  18. Photodynamic therapy with fullerenes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicole LeviCenter for Nanotechnology and Molecular Materials and Department of Physics, Wake Forest University, Winston-Salem, NC 27105, USA. levinh3@wfu.edu
Roy R Hantgan
Mark O Lively
David L Carroll
Gaddamanugu L Prasad
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
NCI NIH HHS P30 CA012197
6 · The paper itself

Abstract

We have developed a new method of application of C60 to cultured cells that does not require water-solubilization techniques. Normal and malignant cells take-up C60 and the inherent photoluminescence of C60 is detected within multiple cell lines. Treatment of cells with up to 200 microg/ml (200 ppm) of C60 does not alter morphology, cytoskeletal organization, cell cycle dynamics nor does it inhibit cell proliferation. Our work shows that pristine C60 is non-toxic to the cells, and suggests that fullerene-based nanocarriers may be used for biomedical applications.

Identifiers

PMID17169152
PMCPMC1764419
OpenAlexW2118651468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.