ReviewArthritis research & therapy2006
What is MRI bone oedema in rheumatoid arthritis and why does it matter?
Review in Arthritis research & therapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed.
- Exploratory analyses of the association of MRI with clinical, laboratory and radiographic findings in patients with rheumatoid arthritis.Annals of the rheumatic diseases · 2011Trial
- The usefulness of magnetic resonance imaging of the hand and wrist in very early rheumatoid arthritis.Arthritis research & therapy · 2011Trial
- Observational
- Limited discriminatory value of RAMRIS findings between RA and hand osteoarthritis: a cross-sectional MRI study.Rheumatology international · 2026Article
- The fate of bone marrow edema after core decompression and bone marrow aspiration concentrate grafting for the hip.BMC musculoskeletal disorders · 2025Article
- Beyond the Signal: Imaging Insights and Diagnostic Relevance of Bone Oedema in Bone Tumours and Tumour-like Lesions.Cancers · 2025Review
- Machine Learning Algorithm: Texture Analysis in CNO and Application in Distinguishing CNO and Bone Marrow Growth-Related Changes on Whole-Body MRI.Diagnostics (Basel, Switzerland) · 2023Article
- Transient Hip Osteoporosis: Etiopathogenetic, Clinical, and Imaging Approach.Mediterranean journal of rheumatology · 2022Review
- Automated segmentation of magnetic resonance bone marrow signal: a feasibility study.Pediatric radiology · 2022Article
- MRI of Hands with Early Rheumatoid Arthritis: Usefulness of Three-Point Dixon Sequences to Quantitatively Assess Disease Activity.Journal of the Belgian Society of Radiology · 2022Article
- Magnetic resonance imaging of rheumatological diseases.Polish journal of radiology · 2022Review
- Traumatic and non-traumatic bone marrow edema in ankle MRI: a pictorial essay.Insights into imaging · 2020Review
- Prevalence and frequency of subchondral bone marrow edema in the lumbar facet joints of asymptomatic and symptomatic individuals.Skeletal radiology · 2020Article
- Overproduced bone marrow neutrophils in collagen-induced arthritis are primed for NETosis: An ignored pathological cell involving inflammatory arthritis.Cell proliferation · 2020Article
- CD4Cells · 2020Article
- The role of advanced MRI in the development of treat-to-target therapeutic strategies, patient stratification and phenotyping in rheumatoid arthritis.BMC rheumatology · 2020Article
- MR and ultrasound of the hands and wrists in rheumatoid arthritis. Part II. Added clinical value.Skeletal radiology · 2019Review
- MRI and ultrasound of the hands and wrists in rheumatoid arthritis. I. Imaging findings.Skeletal radiology · 2019Review
- The value of the simplified RAMRIS-5 in early RA patients under methotrexate therapy using high-field MRI.Arthritis research & therapy · 2019Article
- Rheumatoid Arthritis of Knee Joints: MRI-Pathological Correlation.Orthopaedic surgery · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MRI bone oedema occurs in various forms of inflammatory and non-inflammatory arthritis and probably represents a cellular infiltrate within bone. It is common in early rheumatoid arthritis and is associated with erosive progression and poor functional outcome. Histopathological studies suggest that a cellular infiltrate comprising lymphocytes and osteoclasts may be detected in subchondral bone and could mediate the development of erosions from the marrow towards the joint surface. There is emerging evidence from animal models that such an infiltrate corresponds with MRI bone oedema, pointing towards the bone marrow as a site for important pathology driving joint damage in rheumatoid arthritis.
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Registered trials
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