Evidence map›Paper›PMID 17168773›Full record

ArticleCurrent pharmaceutical design2006

Colloidal microgels in drug delivery applications.

Serguei V Vinogradov

Open access · greenAbstract read
In one paragraph

Article in Current pharmaceutical design, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 211 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Perspectives on Multiscale Colloid-Based Materials for Biomedical Applications.Langmuir : the ACS journal of surfaces and colloids · 2023
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. FRET theoretical predictions concerning freely diffusive dyes inside spherical container: how to choose the best pair?Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Serguei V VinogradovCenter for Drug Delivery and Nanomedicine and Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA. vinograd@unmc.edu
University of Nebraska Medical Center · US

Funding

Polymer-Nucleotide Complexes with Cytotoxic ActivityR01CA102791 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VINOGRADOV, SERGUEI V · 2004 to 2007
$931k
Bioengineering of the blood-brain barrier permeabilityR01NS050660 · NINDS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VINOGRADOV, SERGUEI V · 2005 to 2008
$813k
NCI NIH HHS CA102791NCI NIH HHS R01 CA102791NINDS NIH HHS NS050660NINDS NIH HHS R01 NS050660
6 · The paper itself

Abstract

Colloidal microgels have recently received attention as environmentally responsive systems and now are increasingly used in applications as carriers for therapeutic drugs and diagnostic agents. Synthetic microgels consist of a crosslinked polymer network that provides a depot for loaded drugs, protection against environmental hazards and template for post-synthetic modification or vectorization of the drug carriers. The aim of this manuscript is to review recent attempts to develop new microgel formulations for oral drug delivery, to design metal-containing microgels for diagnostic and therapeutic applications, and to advance approaches including the systemic administration of microgels. Novel nanogel drug delivery systems developed in the authors' laboratory are discussed in details including aspects of their synthesis, vectorization and recent applications for encapsulation of low molecular weight drugs or formulation of biological macromolecules. The findings reviewed here are encouraging for further development of the nanogels as intelligent drug carriers with such features as targeted delivery and triggered drug release.

Indexed as

ColloidsDrug CarriersDrug Delivery SystemsNanotechnologyAdministration, OralAnimalsChemistry, PharmaceuticalDelayed-Action PreparationsDNADrug CompoundingHumansHydrogelsMetalsMucinsNanogelsPharmaceutical PreparationsColloidsDelayed-Action PreparationsDNADrug CarriersHydrogelsMetalsMucinsNanogelsPharmaceutical Preparationspolyethylene glycol polyethyleneimine nanogelPolyethylene GlycolsPolyethyleneiminePolymers

Identifiers

PMID17168773
PMCPMC1764637
OpenAlexW2008380896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.