Evidence map›Paper›PMID 17166507›Full record

ReviewJournal of chromatography. A2007

Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry.

Jose L Luque-Garcia, Thomas A Neubert

Abstract readReview
In one paragraph

Review in Journal of chromatography. A, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. Cancers · 2025
    Review
  12. Article
  13. Article
  14. Mapping the cancer surface proteome in search of target antigens for immunotherapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Improved Screening of Monoclonal Gammopathy Patients by MALDI-TOF Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jose L Luque-GarciaSkirball Institute of Biomolecular Medicine and Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Thomas A Neubert

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
NCI NIH HHS 2P30CA016087-239025
6 · The paper itself

Abstract

In this article, we present an overview of the different strategies for sample preparation for identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We consider the effects of the variables involved in sample collection, handling and storage, and describe different approaches for removal of high abundance proteins and serum/plasma fractionation. We review the advantages and disadvantages of such techniques as centrifugal ultrafiltration, different formats for solid phase extraction, organic solvent extraction, gel and capillary electrophoresis, and liquid chromatography. We also discuss a variety of current proteomic methods and their main applications for biomarker-related studies.

Indexed as

Analytic Sample Preparation MethodsAnticoagulantsBiomarkersBlood Specimen CollectionChemical FractionationChromatography, LiquidElectrophoresis, CapillaryElectrophoresis, Gel, Two-DimensionalGlycoproteinsHumansMagneticsMass SpectrometryProteomicsSolid Phase ExtractionUltrafiltrationAnticoagulantsBiomarkersGlycoproteins

Identifiers

PMID17166507
PMCPMC7094463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.