Evidence map›Paper›PMID 17165150›Full record

ArticleJournal of assisted reproduction and genetics2007

Preferable correlation to blastocyst development and pregnancy rates with a new embryo grading system specific for day 3 embryos.

Masao Nomura, Akira Iwase, Kenji Furui, Takeshi Kitagawa, Yuka Matsui, Manami Yoshikawa, Fumitaka Kikkawa

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Masao NomuraDepartment of Obstetrics and Gynecology, Nagoya University Graduate School Of Medicine, Japan.
Akira Iwase
Kenji Furui
Takeshi Kitagawa
Yuka Matsui
Manami Yoshikawa
Fumitaka Kikkawa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the cleavage stage embryo quality by the correlation between the morphological features and blastocyst development rate to develop a new embryo grading system.

methodsA retrospective analysis, including 216 cycles of cleavage stage embryo transfer and 251 cycles of blastocyst transfer. The correlation with blastocyst development of the embryo cleavage stage, fragmentation and uniformity of blastomeres was evaluated.

resultsThere were significant differences in the blastocyst development rate between > or =7 cells and < or=6 cells (68.8% vs. 30.7%), <50% fragmentation and > or =50% fragmentation (51.9% vs. 25.7%), and evenly sized blastomeres and unevenly sized blastomeres (48.7% vs. 30.1%) on day 3. The new grading system defined by these 3 parameters showed a preferable correlation to the pregnancy rate.

conclusionsThe new grading system specific for day 3 embryos is useful for the selection of good quality embryos and may improve the pregnancy rate.

Indexed as

Embryonic DevelopmentEmbryo TransferAdultBlastocystBlastomeresCleavage Stage, OvumEmbryo ImplantationFemaleHumansPregnancyPregnancy Rate

Identifiers

PMID17165150
PMCPMC3455081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.