ArticleProceedings. Biological sciences2007
Selection against males in Caenorhabditis elegans under two mutational treatments.
Article in Proceedings. Biological sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Males, Outcrossing, and Sexual Selection inGenetics · 2019Review
- Evolution of sex ratio through gene loss.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- A Model for Evolutionary Ecology of Disease: The Case forJournal of nematology · 2017Article
- Experimental Evolution withGenetics · 2017Review
- Female, but not male, nematodes evolve under experimental sexual coevolution.Proceedings. Biological sciences · 2014Article
- The ecology of sexual reproduction.Journal of evolutionary biology · 2014Review
- Mainstreaming Caenorhabditis elegans in experimental evolution.Proceedings. Biological sciences · 2014Review
- The genetic basis and experimental evolution of inbreeding depression in Caenorhabditis elegans.Heredity · 2014Article
- Temporal dynamics of outcrossing and host mortality rates in host-pathogen experimental coevolution.Evolution; international journal of organic evolution · 2013Article
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- Gene conversion and DNA sequence polymorphism in the sex-determination gene fog-2 and its paralog ftr-1 in Caenorhabditis elegans.Molecular biology and evolution · 2010Article
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- Do males facilitate the spread of novel phenotypes within populations of the androdioecious nematode Caenorhabditis elegans?Journal of nematology · 2009Article
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- Experimental insight into the proximate causes of male persistence variation among two strains of the androdioecious Caenorhabditis elegans (Nematoda).BMC ecology · 2008Article
- On the potential for extinction by Muller's ratchet in Caenorhabditis elegans.BMC evolutionary biology · 2008Article
- Rapid experimental evolution of pesticide resistance in C. elegans entails no costs and affects the mating system.PloS one · 2008Article
- Outcrossing and the maintenance of males within C. elegans populations.The Journal of heredityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Within populations with mixed mating systems, selfing is expected to be favoured over outcrossing unless a countervailing process such as severe inbreeding depression is present. In this study, we consider the relationship between the expression of deleterious alleles and the maintenance of outcrossing in the nematode species, Caenorhabditis elegans. This species is characterized by an androdioecious breeding system composed of males at low frequency and self-fertilizing hermaphrodites that can only outcross via males. Here, we find that experimentally increasing the mutational load in four different isogenic wild isolates using 10 generations of Ethylmethane sulphonate (EMS) and UV irradiation mutagenesis significantly diminishes the cost of males. Males are maintained at higher frequencies in mutagenized versus non-mutagenized populations. Nevertheless, males still tend to be driven to low frequencies within isolates that are known to be prone to lose males. Further, we determine the viability effects of a single round of mutagen exposure and find that, for EMS, outcrossing overcomes the almost completely recessive and nearly lethal effects generated. We briefly interpret our results in light of current evolutionary theory of outcrossing rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.