Evidence map›Paper›PMID 17163293›Full record

ArticleClinical drug investigation2006

Resource utilisation and time commitment associated with correction of anaemia in cancer patients using epoetin alfa.

Kenneth R Meehan, N Simon Tchekmedyian, Robert E Smith, Joel Kallich

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical drug investigation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Cost minimization analysis of treatment with intravenous or subcutaneous trastuzumab in patients with HER2-positive breast cancer in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2017
    Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Symptoms and treatment burden associated with cancer treatment: results from a cross-sectional national survey in the U.S.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2008
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kenneth R MeehanBone Marrow Transplant Program, Section of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. Kenneth.Meehan@Hitchcock.org
N Simon Tchekmedyian
Robert E Smith
Joel Kallich
Amgen (United States) · USDartmouth–Hitchcock Medical Center · USSouth Carolina Cancer Alliance · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study set out to identify the resource use and time commitment associated with treatment of anaemia with erythropoietic therapy, for both haematology/oncology clinics and patients.

methodsThe study was carried out at three haematology/oncology clinics in the US, and included 124 cancer patients with anaemia. Stages in the administration of epoetin alfa were identified (preparation, injection and documentation). At each site a trained researcher observed medical staff and recorded the time taken for each stage, in minutes, using a stopwatch. The supplies used for each stage were also recorded. Travel times, waiting times and demographics for patients and caregivers attending the clinic were obtained from self-report questionnaires during the clinic visit. In total, 177 injections of epoetin alfa were administered.

main outcome measureTotal mean time clinic staff and patients spent on treatment visits.

resultsThe total mean time expended by clinic staff for each injection, including preparation, administration, documentation and phlebotomy, was 25.5 minutes (range 18.6-31.2 at individual centres). The total mean time requirement for patients (time spent travelling to and from the clinic, time spent waiting for the epoetin alfa injection) was 83 minutes.

conclusionTreatments that may reduce the time burden of anaemia management should be considered.

Indexed as

AdultAgedAged, 80 and overAnemiaCaregiversCost-Benefit AnalysisEpoetin AlfaErythropoietinFemaleHealth ResourcesHumansMaleMiddle AgedNeoplasmsProspective StudiesRecombinant ProteinsEpoetin AlfaErythropoietinRecombinant Proteins

Identifiers

PMID17163293
OpenAlexW2003225345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.