ArticleJournal of clinical pathology1991
Comparison of commercially available cytokeratin antibodies in normal and neoplastic adult epithelial and non-epithelial tissues.
Article in Journal of clinical pathology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 52 citations in OpenAlex.
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- Breast Cancer Metastasis to the Gastrointestinal Tract After Nine Years of Remission: A Case Report.Cureus · 2026Article
- Detection of Circulating Tumor Cell-Related Markers in Gynecologic Cancer Using Microfluidic Devices: A Pilot Study.International journal of molecular sciences · 2023Article
- Proteomic analysis of tumor tissue in CT-26 implanted BALB/C mouse after treatment with ascorbic acid.Cellular & molecular biology letters · 2012Article
- A rationally designed histone deacetylase inhibitor with distinct antitumor activity against ovarian cancer.Neoplasia (New York, N.Y.) · 2009Article
- Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front.Histochemistry and cell biology · 2008Review
- Breast cancer with an unusual leukemia-like presentation: case report and literature review.Medical oncology (Northwood, London, England) · 2008Article
- Immunohistochemical study of cytoskeletal and extracellular matrix components in the notochord and notochordal sheath of amphioxus.International journal of biological sciences · 2006Article
- [Optimization of staging in colon cancer using sentinel lymph node biopsy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2005Article
- A genetically retargeted adenoviral vector enhances viral transduction in esophageal carcinoma cell lines and primary cultured esophageal resection specimens.Annals of surgery · 2003Article
- Capacity for epithelial differentiation in synovial sarcoma: analysis of a new human cell line.Journal of clinical pathology · 2000Article
- Immunophenotyping of human HT29 colon cancer cell primary tumours and their metastases in severe combined immunodeficient mice.The Histochemical journal · 1997Article
- Cytokeratin demonstration in thick breast tissue slices.The Histochemical journal · 1997Article
- An immunohistochemical study of mesothelial cell seeding for knitted Dacron.International journal of experimental pathology · 1992Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Five commercially available cytokeratin antibodies (lu-5, AE1/AE3, CAM 5.2, MFN116 and anti-cytokeratin 18) were used to stain a wide range of normal and neoplastic epithelial and non-epithelial tissues to assess their potential value in diagnostic histopathology. All five showed good specificity, with some cross-reactivity in smooth muscle cells. The wider reactivity of AE1/AE3, lu-5, and MFN 116, which includes cytokeratins 8,18 (Moll's catalogue) expressed in simple epithelia and their tumours, as well as cytokeratins expressed in complex stratified squamous epithelia, permits identification of a wider range of epithelial derived tumours. This wider spectrum of reactivity may allow these antibodies to be used in a diagnostic panel for the identification of poorly differentiated tumours.
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